| Literature DB >> 19932197 |
Miaozong Wu1, Jacqueline Fannin, Kevin M Rice, Bin Wang, Eric R Blough.
Abstract
Aging is becoming a critical heath care issue and a burgeoning economic burden on society. Mechanotransduction is the ability of the cell to sense, process, and respond to mechanical stimuli and is an important regulator of physiologic function that has been found to play a role in regulating gene expression, protein synthesis, cell differentiation, tissue growth, and most recently, the pathophysiology of disease. Here we will review some of the recent findings of this field and attempt, where possible, to present changes in mechanotransduction that are associated with the aging process in several selected physiological systems, including musculoskeletal, cardiovascular, neuronal, respiratory systems and skin. Published by Elsevier B.V.Entities:
Mesh：
Year: 2009 PMID： 19932197 PMCID： PMC2888727 DOI： 10.1016/j.arr.2009.11.002
Source DB: PubMed Journal: Ageing Res Rev ISSN： 1568-1637 Impact factor: 10.895