Literature DB >> 11824569

Alpha-glucosidase inhibitory constituents from Cuscuta reflexa.

Erum Anis1, Itrat Anis, Saeed Ahmed, Ghulam Mustafa, Abdul Malik, Nighat Afza, Syed Muhammad Abdul Hai, Syed Shahzad-ul-hussan, Muhammad Iqbal Choudhary.   

Abstract

Two new compounds, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (4), and 7'-(4'-hydroxy,3'-methoxyphenyl)-N-[(4-butylphenyl)ethyl]propenamide (5) have been isolated from Cuscuta reflexa along with five known compounds, 6,7-dimethoxy-2H-1-benzopyran-2-one (1), 3-(3,4-dihydroxyphenyl)-2-propen-1-ethanoate (2), 6,7,8-trimethoxy-2H-1-benzopyran-2-one (3), 3-(4-O-beta-D-glucopyranoside-3,5-dimethoxyphenyl)-2-propen-1-ol (6), 2-(3-hydroxy-4-methoxyphenyl)-3,5-dihydroxy-7-O-beta-D-glucopyranoside-4H-1-benzopyrane-4-one (7), reported for the first time from this species. Structures of these compounds were determined by spectral analysis. These compounds showed strong inhibitory activity against alpha-glucosidase.

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Year:  2002        PMID: 11824569     DOI: 10.1248/cpb.50.112

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  9 in total

1.  Effect of Cuscuta reflexa stem and Calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice.

Authors:  Mohammed Rahmatullah; Shamsuddin Sultan; Tanzila Taher Toma; Sayeda-A-Safa Lucky; Majeedul H Chowdhury; Wahid Mozammel Haque; Eashmat Ara Annay; Rownak Jahan
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-12-30

Review 2.  Antidiabetic plant-derived nutraceuticals: a critical review.

Authors:  Jayapal Naveen; Vallikannan Baskaran
Journal:  Eur J Nutr       Date:  2017-10-11       Impact factor: 5.614

3.  Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations.

Authors:  Asaad Khalid; Mohnad Abdalla; Maria Saeed; Muhammad Nabeel Ghayur; Surya Kant Kalauni; Mohammed Albratty; Hassan A Alhazmi; Mohammed Ahmed Mesaik; Anwarul Hassan Gilani; Zaheer Ul-Haq
Journal:  Molecules       Date:  2022-05-24       Impact factor: 4.927

4.  Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities.

Authors:  Patrick C Still; Bitna Yi; Tatiana F González-Cestari; Li Pan; Ryan E Pavlovicz; Hee-Byung Chai; Tran Ngoc Ninh; Chenglong Li; Djaja Djendoel Soejarto; Dennis B McKay; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2013-01-17       Impact factor: 4.050

5.  α-glucosidase inhibitors from plants: A natural approach to treat diabetes.

Authors:  Sunil Kumar; Smita Narwal; Vipin Kumar; Om Prakash
Journal:  Pharmacogn Rev       Date:  2011-01

6.  Cuscuta reflexa and Carthamus Oxyacantha: potent sources of alternative and complimentary drug.

Authors:  Muhammad Asam Raza; Fareeha Mukhtar; Muhammad Danish
Journal:  Springerplus       Date:  2015-02-11

7.  Four new pentasaccharide resin glycosides from Ipomoea cairica with strong α-glucosidase inhibitory activity.

Authors:  Jie-Tao Pan; Bang-Wei Yu; Yong-Qin Yin; Jie-Hong Li; Li Wang; Li-Bing Guo; Zhi-Bin Shen
Journal:  Molecules       Date:  2015-04-14       Impact factor: 4.411

8.  Antidiabetic, antioxidant and antimicrobial activities of extracts of Tephrosia bracteolata leaves.

Authors:  Godshelp Osas Egharevba; Omotayo O Dosumu; Stephen O Oguntoye; Ngaitad S Njinga; Samuel Olatunde Dahunsi; A Abdulmumeen Hamid; Ajay Anand; Zehra Amtul; Priyanka Ujjukuri
Journal:  Heliyon       Date:  2019-08-21

Review 9.  The genus Cuscuta (Convolvolaceac): An updated review on indigenous uses, phytochemistry, and pharmacology.

Authors:  Shazia Noureen; Sobia Noreen; Shazia Akram Ghumman; Fozia Batool; Syed Nasir Abbas Bukhari
Journal:  Iran J Basic Med Sci       Date:  2019-11       Impact factor: 2.699

  9 in total

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