Literature DB >> 1182343

Meiosis: a prostaglandin response that is not inhibited by aspirin.

P G Dellow, T S Miles.   

Abstract

Antidromic stimulation of the sensory nerve to the rabbit eye produces pupillary meiosis, supposedly by release of prostaglandins into the aqueous humour. The analogy between this phenomenon and neurogenic inflammation is drawn. It is shown that aspirin and indomethacin, known blockers of prostaglandin synthesis and release, fail to block the meiosis thus produced.

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Year:  1975        PMID: 1182343      PMCID: PMC1666705          DOI: 10.1111/j.1476-5381.1975.tb07624.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  12 in total

1.  SMOOTH MUSCLE STIMULATING LIPIDS IN SHEEP IRIS. THE IDENTIFICATION OF PROSTAGLANDIN F 2A. PROSTAGLANDINS AND RELATED FACTORS 21.

Authors:  E ANGGARD; B SAMUELSSON
Journal:  Biochem Pharmacol       Date:  1964-02       Impact factor: 5.858

2.  EFFECT OF MECHANICAL STIMULATION ON RABBITS' EYES: RELEASE OF ACTIVE SUBSTANCE IN ANTERIOR CHAMBER PERFUSATES.

Authors:  N AMBACHE; L KAVANAGH; J WHITING
Journal:  J Physiol       Date:  1965-02       Impact factor: 5.182

3.  Influence of the fifth cranial nerve on the intra-ocular pressure of the rabbit eye.

Authors:  E S PERKINS
Journal:  Br J Ophthalmol       Date:  1957-05       Impact factor: 4.638

4.  Aspirin prevents the disruption of the blood-aqueous barrier in the rabbit eye.

Authors:  A H Neufeld; L M Jampol; M L Sears
Journal:  Nature       Date:  1972-07-21       Impact factor: 49.962

5.  The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat.

Authors:  N Jancsó; A Jancsó-Gábor; J Szolcsányi
Journal:  Br J Pharmacol Chemother       Date:  1968-05

6.  Aspirin selectively inhibits prostaglandin production in human platelets.

Authors:  J B Smith; A L Willis
Journal:  Nat New Biol       Date:  1971-06-23

7.  Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

Authors:  J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

8.  Indomethacin and aspirin abolish prostaglandin release from the spleen.

Authors:  S H Ferreira; S Moncada; J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

9.  Consensual ocular hypertensive response to prostaglandin.

Authors:  T S Chiang; R P Thomas
Journal:  Invest Ophthalmol       Date:  1972-03

10.  Failure of intravenous aspirin to increase gastrointestinal blood loss.

Authors:  A R Cooke; K Goulston
Journal:  Br Med J       Date:  1969-08-09
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  2 in total

1.  Prostaglandins and ocular inflammation.

Authors:  D W Hall; I L Bonta
Journal:  Doc Ophthalmol       Date:  1977-12-30       Impact factor: 2.379

2.  Anti-inflammatory drugs, prostaglandins and leucocyte migration.

Authors:  J R Walker; M J Smith; A W Ford-Hutchinson
Journal:  Agents Actions       Date:  1976-09
  2 in total

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