Literature DB >> 11815591

Modulation of oxidative burst of neutrophils by doxycycline in patients with acute myocardial infarction.

Satoshi Takeshita1, Yasuo Ono, Ken Kozuma, Masatoshi Suzuki, Yutaka Kawamura, Naoyuki Yokoyama, Taiji Furukawa, Takaaki Isshiki.   

Abstract

We investigated to what extent doxycycline hydrochloride (DOXY) can modify polymorphonuclear leucocyte (PMN) activity in patients with acute myocardial infarction (AMI). PMN activity was measured in blood samples obtained at 0, 15, 30 and 60 min after DOXY administration. In patients receiving saline, PMN activity did not change over 60 min. In contrast, patients receiving DOXY showed a > or = 10% reduction in PMN activity at 30 and 60 min. These data support the use of DOXY to reduce myocardial cell damage by PMNs in patients with AMI.

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Year:  2002        PMID： 11815591     DOI： 10.1093/jac/49.2.411

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  6 in total

1.  LNK deficiency promotes acute aortic dissection and rupture.

Authors:  Fanny Laroumanie; Arina Korneva; Matthew R Bersi; Matthew R Alexander; Liang Xiao; Xue Zhong; Justin P Van Beusecum; Yuhan Chen; Mohamed A Saleh; William G McMaster; Kyle A Gavulic; Bethany L Dale; Shilin Zhao; Yan Guo; Yu Shyr; Daniel S Perrien; Nancy J Cox; John A Curci; Jay D Humphrey; Meena S Madhur
Journal:  JCI Insight       Date:  2018-10-18

2.  Tetracycline attenuates calcifying nanoparticles-induced renal epithelial injury through suppression of inflammation, oxidative stress, and apoptosis in rat models.

Authors:  Yuqing Zhang; Rujian Zhu; Dong Liu; Min Gong; Wei Hu; Qingtong Yi; Jie Zhang
Journal:  Transl Androl Urol       Date:  2019-12

3.  Antibiotics for secondary prevention of coronary heart disease.

Authors:  Naqash J Sethi; Sanam Safi; Steven Kwasi Korang; Asbjørn Hróbjartsson; Maria Skoog; Christian Gluud; Janus C Jakobsen
Journal:  Cochrane Database Syst Rev       Date:  2021-02-23

4.  Doxycycline-mediated effects on persistent symptoms and systemic cytokine responses post-neuroborreliosis: a randomized, prospective, cross-over study.

Authors:  Johanna Sjöwall; Anna Ledel; Jan Ernerudh; Christina Ekerfelt; Pia Forsberg
Journal:  BMC Infect Dis       Date:  2012-08-10       Impact factor: 3.090

5.  Minocycline inhibits alkali burn-induced corneal neovascularization in mice.

Authors:  Ou Xiao; Zhao-lian Xie; Bin-wu Lin; Xiao-fang Yin; Rong-biao Pi; Shi-you Zhou
Journal:  PLoS One       Date:  2012-07-25       Impact factor: 3.240

Review 6.  The Development of Third-Generation Tetracycline Antibiotics and New Perspectives.

Authors:  Aura Rusu; Emanuela Lorena Buta
Journal:  Pharmaceutics       Date:  2021-12-05       Impact factor: 6.321
  6 in total

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