Literature DB >> 11814839

Solid-phase synthesis of alpha-substituted 3-bisarylthio N-hydroxy propionamides as specific MMP inhibitors.

Anne-Marie Chollet1, Thierry Le Diguarher, Nathalie Kucharczyk, Armelle Loynel, Marc Bertrand, Gordon Tucker, Nicolas Guilbaud, Mike Burbridge, Philippe Pastoureau, Armel Fradin, Massimo Sabatini, Jean-Luc Fauchère, Patrick Casara.   

Abstract

A novel series of potent and specific MMP-2,3,9,13 inhibitors has been obtained by modulation on solid phase by alpha and aryl substitutions on 3-arylthio-N-hydroxy-propionamides starting from itaconic acid.

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Year:  2002        PMID: 11814839     DOI: 10.1016/s0968-0896(01)00311-x

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

Review 1.  An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives.

Authors:  Anna Wójcicka; Aleksandra Redzicka
Journal:  Pharmaceuticals (Basel)       Date:  2021-04-11

2.  3-[(R)-1-Hy-droxy-butan-2-yl]-1,2,3-benzo-triazin-4(3H)-one.

Authors:  Fernando Rocha-Alonzo; David Morales-Morales; Simón Hernández-Ortega; Reyna Reyes-Martínez; Miguel Parra-Hake
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-10-31
  2 in total

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