Literature DB >> 11814599

Genetic information and the family: are we our brother's keeper?

Bartha Maria Knoppers1.   

Abstract

Nowhere are the principles of autonomy and privacy more frequently underscored than in the context of modern human genetics. Fear of untoward socioeconomic and psychosocial consequences of genetic knowledge has reinforced the need for medical confidentiality. However, genetic information is necessarily familial and the needs and interests of other family members cannot be ignored. The past decade has witnessed a gradual move away from the status quo position of absolute confidentiality, to an intermediary position of it being the duty of the patient, to a position making it ethically permissible for the physician to warn in certain limited circumstances. Founded on the principle of mutuality, this last position will revolutionize not only the physician-patient relationship but also the modern, nuclear family.

Entities:  

Keywords:  Genetics and Reproduction

Mesh:

Year:  2002        PMID: 11814599     DOI: 10.1016/s0167-7799(01)01879-0

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  20 in total

1.  Concern for families and individuals in clinical genetics.

Authors:  M Parker; A Lucassen
Journal:  J Med Ethics       Date:  2003-04       Impact factor: 2.903

Review 2.  Ethical reflections on pharmacogenetics and DNA banking in a cohort of HIV-infected patients.

Authors:  Sandrine de Montgolfier; Grégoire Moutel; Nathalie Duchange; Ioannis Theodorou; Christian Hervé; Catherine Leport
Journal:  Pharmacogenetics       Date:  2002-12

Review 3.  Genetic information: a joint account?

Authors:  Michael Parker; Anneke M Lucassen
Journal:  BMJ       Date:  2004-07-17

Review 4.  Research ethics and the challenge of whole-genome sequencing.

Authors:  Amy L McGuire; Timothy Caulfield; Mildred K Cho
Journal:  Nat Rev Genet       Date:  2008-02       Impact factor: 53.242

5.  Should physicians warn patients' relatives of genetic risks?

Authors:  Mireille Lacroix; Gillian Nycum; Béatrice Godard; Bartha Maria Knoppers
Journal:  CMAJ       Date:  2008-02-26       Impact factor: 8.262

6.  Public perceptions of ethical issues regarding adult predictive genetic testing.

Authors:  Douglas K Martin; Heather L Greenwood; Jeff Nisker
Journal:  Health Care Anal       Date:  2009-03-14

7.  Ethical issues in pediatric pharmacogenomics.

Authors:  Kyle B Brothers
Journal:  J Pediatr Pharmacol Ther       Date:  2013-07

8.  Genetic Privacy, Disease Prevention, and the Principle of Rescue.

Authors:  Madison K Kilbride
Journal:  Hastings Cent Rep       Date:  2018-05       Impact factor: 2.683

9.  Informing family members of individuals with Lynch syndrome: a guideline for clinical geneticists.

Authors:  Fred H Menko; Cora M Aalfs; Lidewij Henneman; Yrrah Stol; Miranda Wijdenes; Ellen Otten; Marleen M J Ploegmakers; Johan Legemaate; Ellen M A Smets; Guido M W R de Wert; Aad Tibben
Journal:  Fam Cancer       Date:  2013-06       Impact factor: 2.375

10.  Using a family systems approach to investigate cancer risk communication within melanoma families.

Authors:  Julie N Harris; Jennifer Hay; Alan Kuniyuki; Maryam M Asgari; Nancy Press; Deborah J Bowen
Journal:  Psychooncology       Date:  2010-10       Impact factor: 3.894

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