Literature DB >> 11809558

Use of naloxone in valproic acid overdose: case report and review.

Raymond J Roberge1, Earlie H Francis.   

Abstract

We present a case of a mixed ingestion of valproic acid, gabapentin, mexilitine, and ethanol with central nervous system depression that was reversed by naloxone. This report represents the fourth case demonstrating the antidotal efficacy of naloxone in reversing central nervous system depression associated with acute valproic acid overdose. Increasing clinical experience will more fully elucidate indications for, and optimal dosing of, naloxone in valproic acid toxic states.

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Year:  2002        PMID: 11809558     DOI: 10.1016/s0736-4679(01)00438-3

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  6 in total

Review 1.  Abuse and Misuse of Pregabalin and Gabapentin.

Authors:  Kirk E Evoy; Megan D Morrison; Stephen R Saklad
Journal:  Drugs       Date:  2017-03       Impact factor: 9.546

2.  Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties.

Authors:  José Christian Machado Ximenes; Danilo de Oliveira Gonçalves; Rafaelly Maria Pinheiro Siqueira; Kelly Rose Tavares Neves; Gilberto Santos Cerqueira; Alyne Oliveira Correia; Francisco Hélder Cavalcante Félix; Luzia Kalyne Almeida Moreira Leal; Gerly Anne de Castro Brito; Maria da Graça Naffah-Mazzacorati; Glauce Socorro de Barros Viana
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-04-14       Impact factor: 3.000

Review 3.  Gabapentin misuse, abuse and diversion: a systematic review.

Authors:  Rachel V Smith; Jennifer R Havens; Sharon L Walsh
Journal:  Addiction       Date:  2016-03-18       Impact factor: 6.526

4.  Favorable results after conservative management of 316 valproate intoxicated patients.

Authors:  Shahin Shadnia; Hasan Amiri; Hossein Hassanian-Moghaddam; Mahdi Rezai; Zohreh Vasei; Nillofar Ghodrati; Nasim Zamani
Journal:  J Res Med Sci       Date:  2015-07       Impact factor: 1.852

Review 5.  [Cardiac arrest under special circumstances].

Authors:  Carsten Lott; Anatolij Truhlář; Anette Alfonzo; Alessandro Barelli; Violeta González-Salvado; Jochen Hinkelbein; Jerry P Nolan; Peter Paal; Gavin D Perkins; Karl-Christian Thies; Joyce Yeung; David A Zideman; Jasmeet Soar
Journal:  Notf Rett Med       Date:  2021-06-10       Impact factor: 0.826

6.  Use of naloxone in valproate overdose.

Authors:  Hossein Sanaei-Zadeh
Journal:  Indian J Crit Care Med       Date:  2012-10
  6 in total

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