Literature DB >> 11809067

Theopederins K and L. Highly potent cytotoxic metabolites from a marine sponge Discodermia species.

Gopal K Paul1, Sarath P Gunasekera, Ross E Longley, Shirley A Pomponi.   

Abstract

Theopederins K (1) and L (2) have been isolated from the marine sponge Discodermia sp. collected from Honduras. 1 and 2 showed in vitro cytotoxicity against P-388 and A-549 cell lines. The isolation, biological activities, and structure elucidation of theopederins K (1) and L (2) are described.

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Year:  2002        PMID： 11809067     DOI： 10.1021/np0103766

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  Studies toward the asymmetric synthesis of the right part of the mycalamides.

Authors:  H Marlon Zhong; Jeong-Hun Sohn; Viresh H Rawal
Journal:  J Org Chem       Date:  2007-01-19       Impact factor: 4.354

2.  INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS.

Authors:  Tadeusz F Molinski; Brandon I Morinaka
Journal:  Tetrahedron       Date:  2012-11-18       Impact factor: 2.457

3.  Antineoplastic agents. 542. Isolation and structure of sesterstatin 6 from the Indian Ocean sponge Hyrtios erecta.

Authors:  George R Pettit; Rui Tan; Zbigniew A Cichacz
Journal:  J Nat Prod       Date:  2005-08       Impact factor: 4.050

4.  Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting.

Authors:  Katja M Fisch; Cristian Gurgui; Nina Heycke; Sonia A van der Sar; Sally A Anderson; Victoria L Webb; Stefan Taudien; Matthias Platzer; Brent K Rubio; Sarah J Robinson; Phillip Crews; Jörn Piel
Journal:  Nat Chem Biol       Date:  2009-07       Impact factor: 15.040

Review 5.  Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolide.

Authors:  John H Miller; A Jonathan Singh; Peter T Northcote
Journal:  Mar Drugs       Date:  2010-03-31       Impact factor: 5.118

6.  Inhibition of IL-8 secretion on BxPC-3 and MIA PaCa-2 cells and induction of cytotoxicity in pancreatic cancer cells with marine natural products.

Authors:  Esther A Guzmán; Dedra Harmody; Tara P Pitts; Brunilda Vera-Diaz; Priscilla L Winder; Yichao Yu; Amy E Wright
Journal:  Anticancer Drugs       Date:  2017-02       Impact factor: 2.389

Review 7.  Natural products from the Lithistida: a review of the literature since 2000.

Authors:  Priscilla L Winder; Shirley A Pomponi; Amy E Wright
Journal:  Mar Drugs       Date:  2011-12-15       Impact factor: 6.085

8.  Investigating the structure-activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors.

Authors:  Amr El-Demerdash; Ahmed A Al-Karmalawy; Tarek Mohamed Abdel-Aziz; Sameh S Elhady; Khaled M Darwish; Ahmed H E Hassan
Journal:  RSC Adv       Date:  2021-09-22       Impact factor: 4.036

Review 9.  Predominately Uncultured Microbes as Sources of Bioactive Agents.

Authors:  David J Newman
Journal:  Front Microbiol       Date:  2016-11-18       Impact factor: 5.640
  9 in total

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