PURPOSE: To determine the influence of technical pitfalls and oocyte morphology on survival rate and cleavage behavior after ICSI. METHODS: A total of 2210 injection procedures was examined for morphological and technical deviations. Survival rate and cleavage behavior were evaluated. RESULTS: In 77.8% of all cases ICSI was unsuspicous. Out of 491 deviations from optimal injection deep penetration of the oocyte and abundant presence of cumulus cells showed significant correlation with degeneration rate (p < 0.001). Morphological anomalies associated with the periphery of the oocyte were rather related to degeneration than cytoplasmic anomalies (p < 0.001). Early embryonic development was not impaired by technical or morphological parameters. CONCLUSIONS: To conclude, these prospective data may be of prognostic value in regard of the number of embryos available for transfer and may help to improve treatment outcome.
PURPOSE: To determine the influence of technical pitfalls and oocyte morphology on survival rate and cleavage behavior after ICSI. METHODS: A total of 2210 injection procedures was examined for morphological and technical deviations. Survival rate and cleavage behavior were evaluated. RESULTS: In 77.8% of all cases ICSI was unsuspicous. Out of 491 deviations from optimal injection deep penetration of the oocyte and abundant presence of cumulus cells showed significant correlation with degeneration rate (p < 0.001). Morphological anomalies associated with the periphery of the oocyte were rather related to degeneration than cytoplasmic anomalies (p < 0.001). Early embryonic development was not impaired by technical or morphological parameters. CONCLUSIONS: To conclude, these prospective data may be of prognostic value in regard of the number of embryos available for transfer and may help to improve treatment outcome.
Authors: E Katz; L D Watts; K E Wright; F C Bennett; J L Litz; M D Damewood; M G Compton; J E García Journal: J Assist Reprod Genet Date: 1996-07 Impact factor: 3.412
Authors: Z P Nagy; J Liu; H Joris; G Bocken; B Desmet; H Van Ranst; A Vankelecom; P Devroey; A C Van Steirteghem Journal: Hum Reprod Date: 1995-12 Impact factor: 6.918
Authors: Kevin S Richter; Alana Davis; Jennifer Carter; Stephen J Greenhouse; Gilbert L Mottla; Michael J Tucker Journal: J Exp Clin Assist Reprod Date: 2006-07-05
Authors: Daniela Paes de Almeida Ferreira Braga; Tatiana Carvalho de Souza Bonetti; Ismael Dale Cotrim Guerreiro da Silva; Amanda Souza Setti; Assumpto Jr Iaconelli; Edson Jr Borges Journal: Int J Fertil Steril Date: 2013-03-03