Literature DB >> 11807975

Abietic acid inhibits lipoxygenase activity.

N Nuray Ulusu1, Dilek Ercil, M Koray Sakar, E Ferhan Tezcan.   

Abstract

In this study, it was shown that abietic acid, an abietane diterpenoid, inhibited soybean 5-lipoxygenase (linoleate: oxygen oxidoreductase, EC 1.13.11.12) and an IC(50) of 29.5 +/- 1.29 microM was determined. Since the lipoxygenase pathway leads to the biosynthesis of leukotrienes this result supports the view that abietic acid may be used in the treatment of allergic reactions. Copyright 2002 John Wiley & Sons, Ltd.

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Year:  2002        PMID： 11807975     DOI： 10.1002/ptr.983

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  9 in total

1.  Cerumen of Australian stingless bees (Tetragonula carbonaria): gas chromatography-mass spectrometry fingerprints and potential anti-inflammatory properties.

Authors:  Flavia Carmelina Massaro; Peter Richard Brooks; Helen Margaret Wallace; Fraser Donald Russell
Journal:  Naturwissenschaften       Date:  2011-02-24

2.  A cytochrome P450 involved in the metabolism of abietane diterpenoids by Pseudomonas abietaniphila BKME-9.

Authors:  Daryl J Smith; Vincent J J Martin; William W Mohn
Journal:  J Bacteriol       Date:  2004-06       Impact factor: 3.490

3.  7-Hy-droxy-8-isopropyl-1,1,4a-trimethyl-4a,9,10,10a-tetra-hydro-phenanthren-2(1H)-one.

Authors:  Ahmed Benharref; Essêdiya Lassaba; Noureddine Mazoir; Jean-Claude Daran; Moha Berraho
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-03-19

4.  Synthetic Studies on Tricyclic Diterpenoids: Direct Allylic Amination Reaction of Isopimaric Acid Derivatives.

Authors:  Mariya A Timoshenko; Yurii V Kharitonov; Makhmut M Shakirov; Irina Yu Bagryanskaya; Elvira E Shults
Journal:  ChemistryOpen       Date:  2015-10-28       Impact factor: 2.911

Review 5.  Curious Cases of the Enzymes.

Authors:  Nuriye Nuray Ulusu
Journal:  J Med Biochem       Date:  2015-07-14       Impact factor: 3.402

6.  High-Throughput 1H-Nuclear Magnetic Resonance-Based Screening for the Identification and Quantification of Heartwood Diterpenic Acids in Four Black Pine (Pinus nigra Arn.) Marginal Provenances in Greece.

Authors:  Kostas Ioannidis; Eleni Melliou; Prokopios Magiatis
Journal:  Molecules       Date:  2019-10-07       Impact factor: 4.411

Review 7.  Plant Secondary Metabolites Produced in Response to Abiotic Stresses Has Potential Application in Pharmaceutical Product Development.

Authors:  Karma Yeshi; Darren Crayn; Edita Ritmejerytė; Phurpa Wangchuk
Journal:  Molecules       Date:  2022-01-05       Impact factor: 4.411

8.  Antinociceptive and antitumor activity of novel synthetic mononuclear Ruthenium (II) compounds.

Authors:  Shyam Sunder A; Satyavati Dhulipala; Sreekanth Thota; Rajeshwar Yerra; Jan Balzarini; Erik De Clercq
Journal:  J Res Med Sci       Date:  2013-03       Impact factor: 1.852

9.  The conifer biomarkers dehydroabietic and abietic acids are widespread in Cyanobacteria.

Authors:  Maria Sofia Costa; Adriana Rego; Vitor Ramos; Tiago B Afonso; Sara Freitas; Marco Preto; Viviana Lopes; Vitor Vasconcelos; Catarina Magalhães; Pedro N Leão
Journal:  Sci Rep       Date:  2016-03-21       Impact factor: 4.379
  9 in total

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