Literature DB >> 11806850

Family-based tests of association and/or linkage.

J C Whittaker1, A P Morris.   

Abstract

The large literature on family-based tests of association and/or linkage is reviewed, concentrating on the underlying principles and on recent methodological developments. We explain the distinction between testing for association and testing for linkage, and give our views on the circumstances in which each is the appropriate null hypothesis.

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Year:  2001        PMID： 11806850     DOI： 10.1017/S0003480001008818

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN： 0003-4800            Impact factor:   1.670


  4 in total

1.  Estimation and testing of parent-of-origin effects for quantitative traits.

Authors:  John C Whittaker; Neda Gharani; Peter Hindmarsh; Mark I McCarthy
Journal:  Am J Hum Genet       Date:  2003-03-17       Impact factor: 11.025

2.  A novel approach for small sample size family-based association studies: sequential tests.

Authors:  Ozlem Ilk; Farid Rajabli; Dilay Ciglidag Dungul; Hilal Ozdag; Hakki Gokhan Ilk
Journal:  Eur J Hum Genet       Date:  2011-03-23       Impact factor: 4.246

3.  PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size.

Authors:  Kristina Allen-Brady; Jathine Wong; Nicola J Camp
Journal:  BMC Bioinformatics       Date:  2006-04-18       Impact factor: 3.169

4.  A new family-based association test via a least-squares method.

Authors:  Song Yang; Jungnam Joo; Ziding Feng; Jing-Ping Lin
Journal:  BMC Genet       Date:  2005-12-30       Impact factor: 2.797
  4 in total

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