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Literature DB >> 118048

Silymarin, an inhibitor of lipoxygenase.

Abstract

Silybin (I), silydianin (II) and silychristin (III), the constituents of silymarin, non-competitively inhibit the lipoxygenase from soybeans (EC 1.13.11.12) in vitro.

Entities: Chemical Species

Mesh：

Substances：

Year: 1979 PMID： 118048 DOI： 10.1007/bf01953184

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

11 in total

1. The determination of enzyme inhibitor constants.

Authors: M DIXON
Journal: Biochem J Date: 1953-08 Impact factor: 3.857

2. Spectrophotometric Method for Determination of Lipoxidase Activity.

Authors: K Surrey
Journal: Plant Physiol Date: 1964-01 Impact factor: 8.340

3. Lipoperoxidative effects on liver rough microsomal membranes and the ribosome-membrane complex: studies in vitro and in vivo with chemical carcinogens and carbon tetrachloride.

Authors: T K Shires
Journal: Lab Invest Date: 1978-06 Impact factor: 5.662

4. Chemicals, drugs, and lipid peroxidation.

Authors: G L Plaa; H Witschi
Journal: Annu Rev Pharmacol Toxicol Date: 1976 Impact factor: 13.820

5. Iron, an essential component of lipoxygenase.

Authors: E K Pistorius; B Axelrod
Journal: J Biol Chem Date: 1974-05-25 Impact factor: 5.157

6. [The chemistry and analysis of silymarin from Silybum marianum Gaertn].

Authors: H Wagner; P Diesel; M Seitz
Journal: Arzneimittelforschung Date: 1974-04

7. [Silymarin prevents peroxidation of lipids in carbon tetrachloride-induced liver damage].

Authors: H M Rauen; H Schriewer; U Tegtbauer; J E Lasana
Journal: Experientia Date: 1973-11-15

8. A convenient method for lipoxygenase isoenzyme determination.

Authors: S Grossman; A Pinsky; Z Goldweitz
Journal: Anal Biochem Date: 1971-12 Impact factor: 3.365

9. [On the pharmacology and toxicology of silymarin, an antihepatotoxic active principle from Silybum marianum (L.) Gaertn].

Authors: G Hahn; H D Lehmann; M Kürten; H Uebel; G Vogel
Journal: Arzneimittelforschung Date: 1968-06

10. On the specificity of the lipoxidase catalyzed oxygenation of unsaturated fatty acids.

Authors: M Hamberg; B Samuelsson
Journal: Biochem Biophys Res Commun Date: 1965-12-21 Impact factor: 3.575

4 in total

1. The flavonoids: a brief review and study of effects on antigen-induced histamine release from human basophils.

Authors: E Middleton; D G Krishnarao; D Atkins; G Drzewiecki
Journal: Trans Am Clin Climatol Assoc Date: 1981

2. Silymarin, an inhibitor of prostaglandin synthetase.

Authors: F Fiebrich; H Koch
Journal: Experientia Date: 1979-12-15

Review 3. Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions.

Authors: Tomas Koltai; Larry Fliegel
Journal: J Evid Based Integr Med Date: 2022 Jan-Dec

Review 4. A review on the mechanisms of the effect of silymarin in milk thistle (Silybum marianum) on some laboratory animals.

Authors: Roshanak Khazaei; Alireza Seidavi; Mehrdad Bouyeh
Journal: Vet Med Sci Date: 2021-10-02

4 in total