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Literature DB >> 11799195

Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication.

Abstract

Interferon inhibits virus replication through multiple mechanisms. Here we show that herpes simplex virus proteins ICP0 and ICP34.5 overcome interferon-induced barriers to viral transcription and translation, respectively. These cytokine-induced antiviral mechanisms are differentially expressed in established cell lines: U2OS cells do not mount the IFN-induced mechanism targeted by ICP0, and Vero cells may be defective for the mechanism targeted by ICP34.5.

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Year: 2002 PMID： 11799195 PMCID： PMC135894 DOI： 10.1128/jvi.76.4.1995-1998.2002

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

33 in total

1. Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1.

Authors: J Chou; J J Chen; M Gross; B Roizman
Journal: Proc Natl Acad Sci U S A Date: 1995-11-07 Impact factor: 11.205

2. Characterization of the early steps of herpes simplex virus replication in interferon-treated human cells.

Authors: F Oberman; A Panet
Journal: J Interferon Res Date: 1989-10

3. Specific effect of interferon on the herpes simplex virus type 1 transactivation event.

Authors: P R De Stasio; M W Taylor
Journal: J Virol Date: 1990-06 Impact factor: 5.103

4. Differential response of human cells to deletions and stop codons in the gamma(1)34.5 gene of herpes simplex virus.

Authors: J Chou; A P Poon; J Johnson; B Roizman
Journal: J Virol Date: 1994-12 Impact factor: 5.103

5. Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage.

Authors: J Chou; B Roizman
Journal: Proc Natl Acad Sci U S A Date: 1994-06-07 Impact factor: 11.205

6. Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).

Authors: G G Maul; H H Guldner; J G Spivack
Journal: J Gen Virol Date: 1993-12 Impact factor: 3.891

7. ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures.

Authors: C A Bolovan; N M Sawtell; R L Thompson
Journal: J Virol Date: 1994-01 Impact factor: 5.103

8. An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1.

Authors: F Yao; P A Schaffer
Journal: J Virol Date: 1995-10 Impact factor: 5.103

9. Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription.

Authors: S Mittnacht; P Straub; H Kirchner; H Jacobsen
Journal: Virology Date: 1988-05 Impact factor: 3.616

10. The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.

Authors: J Chou; B Roizman
Journal: Proc Natl Acad Sci U S A Date: 1992-04-15 Impact factor: 11.205

66 in total

1. The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes.

Authors: Rongtuan Lin; Ryan S Noyce; Susan E Collins; Roger D Everett; Karen L Mossman
Journal: J Virol Date: 2004-02 Impact factor: 5.103

2. Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products.

Authors: Matthew Mulvey; Vladimir Camarena; Ian Mohr
Journal: J Virol Date: 2004-09 Impact factor: 5.103

3. Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5.

Authors: Junji Xing; Shuai Wang; Rongtuan Lin; Karen L Mossman; Chunfu Zheng
Journal: J Virol Date: 2012-02-01 Impact factor: 5.103

4. Characterization of a potent refractory state and persistence of herpes simplex virus 1 in cell culture.

Authors: Cristina Barreca; Peter O'Hare
Journal: J Virol Date: 2006-09 Impact factor: 5.103

Review 5. A guide to viral inclusions, membrane rearrangements, factories, and viroplasm produced during virus replication.

Authors: Christopher Netherton; Katy Moffat; Elizabeth Brooks; Thomas Wileman
Journal: Adv Virus Res Date: 2007 Impact factor: 9.937