Literature DB >> 11794800

Synthesis and anti-HIV activity of new modified 1,2,3-triazole acyclonucleosides.

H B Lazrek1, M Taourirte, T Oulih, J L Barascut, J L Imbach, C Pannecouque, M Witrouw, E De Clercq.   

Abstract

The synthesis of 1,2,3-triazole acyclonucleosides 7a-h via 1,3-dipolar cycloaddition of N-9/N-1-propargylpurine/pyrimidine 2a-h with azido-pseudo-sugar 4 is described and none of them had anti-HIV activity.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11794800     DOI： 10.1081/NCN-100108325

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  15 in total

1.  Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus.

Authors:  Venkata Ramana Sirivolu; Sanjeev Kumar V Vernekar; Tatiana Ilina; Nataliya S Myshakina; Michael A Parniak; Zhengqiang Wang
Journal:  J Med Chem       Date:  2013-10-28       Impact factor: 7.446

2.  Synthesis of 1,4-disubstituted mono and bis-triazolocarbo-acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine by Cu(I)-catalyzed click azide-alkyne cycloaddition.

Authors:  Jamal Krim; Moha Taourirte; Joachim W Engels
Journal:  Molecules       Date:  2011-12-27       Impact factor: 4.411

3.  Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.

Authors:  Dorota G Piotrowska; Jan Balzarini; Iwona E Głowacka
Journal:  Eur J Med Chem       Date:  2011-11-20       Impact factor: 6.514

4.  Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues.

Authors:  Iwona E Głowacka; Jan Balzarini; Graciela Andrei; Robert Snoeck; Dominique Schols; Dorota G Piotrowska
Journal:  Bioorg Med Chem       Date:  2014-05-20       Impact factor: 3.641

5.  Benzimidazole-1,2,3-triazole hybrid molecules: synthesis and evaluation for antibacterial/antifungal activity.

Authors:  Abdelaaziz Ouahrouch; Hana Ighachane; Moha Taourirte; Joachim W Engels; My Hassan Sedra; Hassan B Lazrek
Journal:  Arch Pharm (Weinheim)       Date:  2014-08-04       Impact factor: 3.751

6.  Synthesis of 1,2,3-triazolyl nucleoside analogues and their antiviral activity.

Authors:  Olga V Andreeva; Bulat F Garifullin; Vladimir V Zarubaev; Alexander V Slita; Iana L Yesaulkova; Liliya F Saifina; Marina M Shulaeva; Maya G Belenok; Vyacheslav E Semenov; Vladimir E Kataev
Journal:  Mol Divers       Date:  2020-09-15       Impact factor: 2.943

7.  Multicomponent click synthesis of new 1,2,3-triazole derivatives of pyrimidine nucleobases: promising acidic corrosion inhibitors for steel.

Authors:  Rodrigo González-Olvera; Araceli Espinoza-Vázquez; Guillermo E Negrón-Silva; Manuel E Palomar-Pardavé; Mario A Romero-Romo; Rosa Santillan
Journal:  Molecules       Date:  2013-12-06       Impact factor: 4.411

8.  Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker.

Authors:  Iwona E Głowacka; Graciela Andrei; Dominique Schols; Robert Snoeck; Dorota G Piotrowska
Journal:  Molecules       Date:  2015-10-16       Impact factor: 4.411

9.  Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides.

Authors:  Iwona E Głowacka; Graciela Andrei; Dominique Schols; Robert Snoeck; Katarzyna Gawron
Journal:  Arch Pharm (Weinheim)       Date:  2017-08-01       Impact factor: 3.751

10.  The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker.

Authors:  Iwona E Głowacka; Jan Balzarini; Andrzej E Wróblewski
Journal:  Eur J Med Chem       Date:  2013-10-30       Impact factor: 6.514
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.