Literature DB >> 1179211

Antibody formation in first and second generation offspring of nutritionally deprived rats.

R K Chandra.   

Abstract

Prolonged partial restriction of calorie intake in young rats results in reduced growth, involution of lymphoid organs, and lymphopenia. After immunization with sheep red blood cells, the number of antibody-forming cells in the spleen and serum hemolysin titers are markedly reduced. The effect is more pronounced on the primary response and on immunoglobulin G antibody-forming cells. Significant impairment of antibody formation is detectable in the first (F1) and second (F2) generation offspring of starved Fo mothers.

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Year:  1975        PMID： 1179211     DOI： 10.1126/science.1179211

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  26 in total

1.  Malnutrition, humoral immunity and infection.

Authors:  R K Chandra; S Chakraburty; S Chandra
Journal:  Indian J Pediatr       Date:  1976-06       Impact factor: 1.967

Review 2.  The mammary gland in mammalian evolution: a brief commentary on some of the concepts.

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Review 3.  Do multiple concurrent infections in African children cause irreversible immunological damage?

Authors:  Sarah J Glennie; Moffat Nyirenda; Neil A Williams; Robert S Heyderman
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Review 4.  Nutritional regulation of immunity and risk of infection in old age.

Authors:  R K Chandra
Journal:  Immunology       Date:  1989-06       Impact factor: 7.397

5.  Effect of malnutrition on K+ current in T lymphocytes.

Authors:  Rafael Godínez Fernández; Joaquín Azpiroz Leehan; Reyna Fierro Pastrana; Rocío Ortíz Muñiz
Journal:  Clin Diagn Lab Immunol       Date:  2005-07

6.  Nutrition and immunity: practical applications of research findings.

Authors:  R K Chandra
Journal:  Can Fam Physician       Date:  1987-06       Impact factor: 3.275

7.  Nutrition, immunity and infection: from basic knowledge of dietary manipulation of immune responses to practical application of ameliorating suffering and improving survival.

Authors:  R K Chandra
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

Review 8.  A theory of technophysio evolution, with some implications for forecasting population, health care costs, and pension costs.

Authors:  R W Fogel; D L Costa
Journal:  Demography       Date:  1997-02

9.  Effect of protein calorie malnutrition on the levels of natural and inducible cytotoxic activities in mouse spleen cells.

Authors:  Q B Saxena; R K Saxena; W H Adler
Journal:  Immunology       Date:  1984-04       Impact factor: 7.397

Review 10.  Spontaneous glomerular sclerosis in aging Sprague-Dawley rats. I. Lesions associated with mesangial IgM deposits.

Authors:  W K Bolton; F R Benton; J G Maclay; B C Sturgill
Journal:  Am J Pathol       Date:  1976-11       Impact factor: 4.307
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