| Literature DB >> 11784171 |
G Gumina1, R F Schinazi, C K Chu.
Abstract
L-2',3'-Didehydro-2',3'-dideoxy-3'-fluorocytidine (L-3'-Fd4C), a novel potent anti-HIV agent (EC(50) 0.03 microM in PBM cells), has been synthesized from L-xylose in 14 steps. [reaction: see text]Entities:
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Year: 2001 PMID： 11784171 DOI： 10.1021/ol0168059
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005