Literature DB >> 11778793

Measurement of peak inhalation rates with an in-check meter to identify an elderly patient's ability to use a turbuhaler.

W M Nsour1, A Alldred, J Corrado, H Chrystyn.   

Abstract

Dry powder inhalers are designed with resistance to airflow so that a respirable cloud of particles is generated during inhalation. Some of these devices require a certain inhalation rate to produce a consistent dose of respirable particles. The aim of the study was to determine the inhalation rate of elderly patients with chronic obstructive pulmonary disease (COPD) when they inhale through a Turbuhaler and assess the potential of the In-Check Meter to identify inhalation rates. Their peak inhalation rate using a normal inhalation, pre- and post-counselling, was measured using a Turbuhaler Trainer and an In-Check Meter. Spirometry was also measured. Seventy-four COPD patients with a mean (SD) age of 79.7 (8.4) years and forced expiratory volume in 1 sec (FEV1) 41.9 (12.8)% predicted. Pre-counselling 14 obtained a rate of <30 l min(-1) with the Turbuhaler Trainer, 31 from 30 to 40 min(-1), 23 between 40-60 l min(-1) and 6 > 60 l min(-1). The median (range) peak inhalation rates with the In-Check Meter were 50 (50-70), 70 (50-130), 100 (60-200) and 225 (200-250) l min(-1). Post-counselling 7, 16,41 and 10 achieved the respective peak inhalation rates using the Turbuhaler Trainer Similarly the In-Check inhalation rates were 50 (50-60), 70 (50-130), 90 (60-200) and 250 (200-270) l min(-1). The results highlight the potential of the In-Check Meter to identify patients' inhalation rates through dry powder inhalers.

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Year:  2001        PMID: 11778793     DOI: 10.1053/rmed.2001.1190

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  10 in total

1.  Personalization of Device Therapy - Prime Time for Peak Inspiratory Flow Rate.

Authors:  Chee H Loh; Jill A Ohar
Journal:  Chronic Obstr Pulm Dis       Date:  2017-07-14

Review 2.  Closer to an 'ideal inhaler' with the Easyhaler: an innovative dry powder inhaler.

Authors:  Henry Chrystyn
Journal:  Clin Drug Investig       Date:  2006       Impact factor: 2.859

3.  Comparing usability of NEXThaler(®) with other inhaled corticosteroid/long-acting β2-agonist fixed combination dry powder inhalers in asthma patients.

Authors:  Thomas Voshaar; Monica Spinola; Patrick Linnane; Alice Campanini; Daniel Lock; Anthony Lafratta; Mario Scuri; Barbara Ronca; Andrea S Melani
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2013-12-03       Impact factor: 2.849

4.  Reduced Peak Inspiratory Effort through the Diskus((R)) and the Turbuhaler((R)) due to Mishandling is Common in Clinical Practice.

Authors:  Andrea S Melani; Letizia S Bracci; Marcello Rossi
Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

5.  Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study.

Authors:  Wahida Azouz; Philip Chetcuti; Harold Hosker; Dinesh Saralaya; Henry Chrystyn
Journal:  BMC Pulm Med       Date:  2015-05-01       Impact factor: 3.317

6.  Peak inspiratory flow rate measurement by using In-Check DIAL for the different inhaler devices in elderly with obstructive airway diseases.

Authors:  Theerasuk Kawamatawong; Supattra Khiawwan; Prapaporn Pornsuriyasak
Journal:  J Asthma Allergy       Date:  2017-02-23

7.  Assessment of inhalation flow patterns of soft mist inhaler co-prescribed with dry powder inhaler using inspiratory flow meter for multi inhalation devices.

Authors:  Daiki Hira; Hiroyoshi Koide; Shigemi Nakamura; Toyoko Okada; Kazunori Ishizeki; Masafumi Yamaguchi; Setsuko Koshiyama; Tetsuya Oguma; Kayoko Ito; Saori Funayama; Yuko Komase; Shin-Ya Morita; Kohshi Nishiguchi; Yasutaka Nakano; Tomohiro Terada
Journal:  PLoS One       Date:  2018-02-20       Impact factor: 3.240

8.  Technical Evaluation of Soft Mist Inhaler Use in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.

Authors:  Wei Zhang; Lili Xu; Shen Gao; Nan Ding; Ping Shu; Zhuo Wang; Yuping Li
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-06-22

9.  Patients with asthma or chronic obstructive pulmonary disease (COPD) can generate sufficient inspiratory flows via Easyhaler® dry powder inhaler: a pooled analysis of two randomized controlled trials.

Authors:  L Pekka Malmberg; Anna S Pelkonen; Ville Vartiainen; Mikko Vahteristo; Satu Lähelmä; Rain Jõgi
Journal:  J Thorac Dis       Date:  2021-02       Impact factor: 3.005

Review 10.  Relationship between Peak Inspiratory Flow and Patient and Disease Characteristics in Individuals with COPD-A Systematic Scoping Review.

Authors:  Marika T Leving; Janwillem Kocks; Sinthia Bosnic-Anticevich; Richard Dekhuijzen; Omar S Usmani
Journal:  Biomedicines       Date:  2022-02-16
  10 in total

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