Literature DB >> 1177668

Enzymatic synthesis of glucocerebroside by UDP-glucose: ceramide glucosyltransferase during ontogenesis of chicken retina.

H Dreyfus, P F Urban, S Edel-Harth, N M Neskovic, P Mandel.   

Abstract

The activity of uridine diphosphate-glucose: ceramide glucosyltransferase during chick retina ontogenesis was studied. This enzyme catalyzes the first step in the biosynthetic pathway leading to gangliosides. The glucosyltransferase activity was detected in 8 day old embryos, and was present in adult animals. The highest specific activity was found ca. day 10 of embryonic life. The radioactive product was identified as glucocerebroside by means of radiochromatography. The presence of phosphatidylcholine in the incubation mixtures was found to stimulate the enzyme.

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Year:  1975        PMID： 1177668     DOI： 10.1007/bf02532358

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  22 in total

1.  The structure of cerebrosides in Gaucher's disease.

Authors:  G V MARINETTI; T FORD; E STOTZ
Journal:  J Lipid Res       Date:  1960-04       Impact factor: 5.922

2.  Enzymatic synthesis of glucocerebroside by a glucosyltransferase from embryonic chicken brain.

Authors:  S Basu; B Kaufman; S Roseman
Journal:  J Biol Chem       Date:  1973-02-25       Impact factor: 5.157

3.  Enzymatic synthesis of ceramide-glucose and ceramide-lactose by glycosyltransferases from embryonic chicken brain.

Authors:  S Basu; B Kaufman; S Roseman
Journal:  J Biol Chem       Date:  1968-11-10       Impact factor: 5.157

4.  Biosynthesis of lactosylceramide by rat brain preparations and comparison with the formation of ganglioside Gm1 and psychosine during development.

Authors:  J Hildebrand; P Stoffyn; G Hauser
Journal:  J Neurochem       Date:  1970-03       Impact factor: 5.372

5.  Synthesis of cerebroside by brain from uridine diphosphate galactose and ceramide containing hydroxy fatty acid.

Authors:  P Morell; N S Radin
Journal:  Biochemistry       Date:  1969-02       Impact factor: 3.162

6.  Glycosyl transferases of microsomal fractions from brain: synthesis of glucosyl ceramide and galactosyl ceramide during development and the distribution of glucose and galactose transferase in white and grey matter.

Authors:  S N Shah
Journal:  J Neurochem       Date:  1971-03       Impact factor: 5.372

7.  Brain glucosyl ceramides containing 2-hydroxy acids. Identification of molecular species by gas-liquid chromatography--mass spectrometry.

Authors:  S Hammarström
Journal:  Eur J Biochem       Date:  1971-08-16

8.  Isolation of cerebroside containing glucose (Glucosyl ceramide) and its possible significance in ganglioside synthesis.

Authors:  K Nishimura; T Yamakawa
Journal:  Lipids       Date:  1968-05       Impact factor: 1.880

9.  Composition of phospholipids and of phospholipid fatty acids and aldehydes in human red cells.

Authors:  J T Dodge; G B Phillips
Journal:  J Lipid Res       Date:  1967-11       Impact factor: 5.922

10.  Separation of gluco- and galactocerebrosides by means of borate thin-layer chromatography.

Authors:  E L Kean
Journal:  J Lipid Res       Date:  1966-05       Impact factor: 5.922
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  2 in total

1.  NMR-based metabolic characterization of chicken tissues and biofluids: a model for avian research.

Authors:  Caroline Ivanne Le Roy; Luke John Mappley; Roberto Marcello La Ragione; Martin John Woodward; Sandrine Paule Claus
Journal:  Metabolomics       Date:  2016-09-15       Impact factor: 4.290

2.  Metabolomics-Based Clinical Efficacy and Effect on the Endogenous Metabolites of Tangzhiqing Tablet, a Chinese Patent Medicine for Type 2 Diabetes Mellitus with Hypertriglyceridemia.

Authors:  Jia Liu; Ziqiang Li; Hua Liu; Xianhua Wang; Chunxiao Lv; Ruihua Wang; Deqin Zhang; Yan Li; Xi Du; Yanfen Li; Baohe Wang; Yuhong Huang
Journal:  Evid Based Complement Alternat Med       Date:  2018-07-24       Impact factor: 2.629
  2 in total

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