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Literature DB >> 11774507

Identification of the mutations responsible for the phenotype of three MHV RNA-negative ts mutants.

S Siddell¹, D Sawicki, Y Meyer, V Thiel, S Sawicki.

Abstract

Mesh：

Substances：
RNA, Viral

Year: 2001 PMID： 11774507 DOI： 10.1007/978-1-4615-1325-4_66

Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622

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14 in total

1. Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.

Authors: Jeremiah S Joseph; Kumar Singh Saikatendu; Vanitha Subramanian; Benjamin W Neuman; Alexei Brooun; Mark Griffith; Kin Moy; Maneesh K Yadav; Jeffrey Velasquez; Michael J Buchmeier; Raymond C Stevens; Peter Kuhn
Journal: J Virol Date: 2006-08 Impact factor: 5.103

2. The nucleoprotein is required for efficient coronavirus genome replication.

Authors: Fernando Almazán; Carmen Galán; Luis Enjuanes
Journal: J Virol Date: 2004-11 Impact factor: 5.103

3. Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo.

Authors: Scott E Coley; Ehud Lavi; Stanley G Sawicki; Li Fu; Barbara Schelle; Nadja Karl; Stuart G Siddell; Volker Thiel
Journal: J Virol Date: 2005-03 Impact factor: 5.103

4. Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication.

Authors: Sarah M Brockway; Xiao Tao Lu; Timothy R Peters; Terence S Dermody; Mark R Denison
Journal: J Virol Date: 2004-11 Impact factor: 5.103

5. Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis.

Authors: Eric F Donaldson; Amy C Sims; Rachel L Graham; Mark R Denison; Ralph S Baric
Journal: J Virol Date: 2007-03-28 Impact factor: 5.103

6. Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing.

Authors: Eric F Donaldson; Rachel L Graham; Amy C Sims; Mark R Denison; Ralph S Baric
Journal: J Virol Date: 2007-04-11 Impact factor: 5.103

Identification of the mutations responsible for the phenotype of three MHV RNA-negative ts mutants.

1. Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.

2. The nucleoprotein is required for efficient coronavirus genome replication.

3. Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo.

4. Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication.

5. Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis.

6. Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing.

Review 7. RNA-RNA and RNA-protein interactions in coronavirus replication and transcription.

8. Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles.

Review 9. SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets.

10. The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein.