| Literature DB >> 11772462 |
Abstract
Biological encapsulation and the foreign body reaction can impair the performance of implanted drug release devices. In this article, the classic definition of biocompatibility is questioned. Examples are presented of biomaterials showing unique healing behavior. A new paradigm for biomaterials healing is proposed in which non-specific protein adsorption is inhibited and matricellular proteins are controlled at the surfaces of implants.Mesh:
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Year: 2002 PMID: 11772462 DOI: 10.1016/s0168-3659(01)00502-8
Source DB: PubMed Journal: J Control Release ISSN: 0168-3659 Impact factor: 9.776