D Scambler1, S J Rogers, E A Wehner. 1. JFK Partners, University of Colorado Health Sciences Center, Denver 80262, USA. doug.scambler@uchsc.edu
Abstract
OBJECTIVE: The Checklist for Autism in Toddlers (CHAT) has been demonstrated to be sensitive to the presence of autism in otherwise normally developing 18-month-old children. However, its ability to differentiate autism from other significant developmental delays is unknown. This study examined this question. METHOD: The CHAT was applied to a group of 44 children aged 2 and 3 years, rigorously diagnosed with autism or with other developmental problems. RESULTS: By the original CHAT authors' criteria, the sensitivity and specificity of the CHAT were 65% and 100%, respectively. Slightly altering the criteria resulted in a sensitivity of 85% in the current group of children with developmental disabilities while maintaining specificity of 100%. CONCLUSIONS: The current study is the first to demonstrate that the CHAT successfully discriminates 2-year-old children with autism from those with other developmental disorders. In addition, the increased sensitivity of the Denver Criteria in children with developmental disabilities may improve its usefulness as a screening tool for community-based early-diagnostic teams and general practitioners.
OBJECTIVE: The Checklist for Autism in Toddlers (CHAT) has been demonstrated to be sensitive to the presence of autism in otherwise normally developing 18-month-old children. However, its ability to differentiate autism from other significant developmental delays is unknown. This study examined this question. METHOD: The CHAT was applied to a group of 44 children aged 2 and 3 years, rigorously diagnosed with autism or with other developmental problems. RESULTS: By the original CHAT authors' criteria, the sensitivity and specificity of the CHAT were 65% and 100%, respectively. Slightly altering the criteria resulted in a sensitivity of 85% in the current group of children with developmental disabilities while maintaining specificity of 100%. CONCLUSIONS: The current study is the first to demonstrate that the CHAT successfully discriminates 2-year-old children with autism from those with other developmental disorders. In addition, the increased sensitivity of the Denver Criteria in children with developmental disabilities may improve its usefulness as a screening tool for community-based early-diagnostic teams and general practitioners.
Authors: Iris J Oosterling; Sophie H Swinkels; Rutger Jan van der Gaag; Janne C Visser; Claudine Dietz; Jan K Buitelaar Journal: J Autism Dev Disord Date: 2009-02-10
Authors: Fabiënne Naber; Marian J Bakermans-Kranenburg; Marinus H van Ijzendoorn; Claudine Dietz; Emma van Daalen; Sophie H N Swinkels; Jan K Buitelaar; Herman van Engeland Journal: Eur Child Adolesc Psychiatry Date: 2008-04 Impact factor: 4.785
Authors: Patricia García-Primo; Annika Hellendoorn; Tony Charman; Herbert Roeyers; Mieke Dereu; Bernadette Roge; Sophie Baduel; Filippo Muratori; Antonio Narzisi; Emma Van Daalen; Irma Moilanen; Manuel Posada de la Paz; Ricardo Canal-Bedia Journal: Eur Child Adolesc Psychiatry Date: 2014-06-10 Impact factor: 4.785