Literature DB >> 11764929

Hemoglobin adducts in rats chronically exposed to room-aged cigarette sidestream smoke and diesel engine exhaust.

R Stabbert1, G Schepers, W S Stinn, H J Haussmann.   

Abstract

Under controlled conditions with exaggerated concentrations of environmental aerosols, the biologically effective dose markers suggested in the literature as being specific for ETS (i.e., HPB Hb adducts for TSNA exposure) and DEE (i.e., l-aminopyrene Hb adducts for l-nitropyrene exposure) did not respond. A slight but dose-dependent increase in 4-ABP Hb adduct levels was seen in RASS-exposed rats.

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Year:  2001        PMID: 11764929     DOI: 10.1007/978-1-4615-0667-6_20

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  2 in total

1.  Sidestream cigarette smoke toxicity increases with aging and exposure duration.

Authors:  Suzaynn F Schick; Suzaynn Schick; Stanton A Glantz
Journal:  Tob Control       Date:  2006-12       Impact factor: 7.552

Review 2.  Philip Morris toxicological experiments with fresh sidestream smoke: more toxic than mainstream smoke.

Authors:  S Schick; S Glantz
Journal:  Tob Control       Date:  2005-12       Impact factor: 7.552

  2 in total

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