Literature DB >> 11759019

Hepatitis A virus: a test method for virucidal activity.

M H Wolff1, J Schmitt, M Rahaus, A König.   

Abstract

Hepatitis A virus (HAV) is closely related to the genus enterovirus. HAV is very stable and resistant to acid pH and elevated temperature, as well as to chemicals and environmental influences. Human poliovirus is still one of the model viruses for testing disinfectants but there are discussions about changing to hepatitis A virus. The purpose of this study was to develop a method for using adapted hepatitis A virus to test hand disinfectants. Using HAV strains HM175/24a and FRhK-4 cytopathic effects were visible rarely, and not before 14 days. To verify virus growth in cells a RT-PCR was developed. Two disinfectants tested did not show the required virucidal activity to satisfy current German guidelines.

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Year:  2001        PMID： 11759019     DOI： 10.1016/s0195-6701(01)90007-6

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN： 0195-6701            Impact factor:   3.926


  9 in total

Review 1.  Persistence of Hepatitis A Virus in Fresh Produce and Production Environments, and the Effect of Disinfection Procedures: A Review.

Authors:  N Cook; I Bertrand; C Gantzer; R M Pinto; A Bosch
Journal:  Food Environ Virol       Date:  2018-05-14       Impact factor: 2.778

Review 2.  Ethanol is indispensable for virucidal hand antisepsis: memorandum from the alcohol-based hand rub (ABHR) Task Force, WHO Collaborating Centre on Patient Safety, and the Commission for Hospital Hygiene and Infection Prevention (KRINKO), Robert Koch Institute, Berlin, Germany.

Authors:  Axel Kramer; Mardjan Arvand; Bärbel Christiansen; Stephanie Dancer; Maren Eggers; Martin Exner; Dieter Müller; Nico T Mutters; Ingeborg Schwebke; Didier Pittet
Journal:  Antimicrob Resist Infect Control       Date:  2022-07-06       Impact factor: 6.454

Review 3.  Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs.

Authors:  Günter Kampf; Axel Kramer
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

Review 4.  Don't Shut the Stable Door after the Phage Has Bolted-The Importance of Bacteriophage Inactivation in Food Environments.

Authors:  Julia Sommer; Christoph Trautner; Anna Kristina Witte; Susanne Fister; Dagmar Schoder; Peter Rossmanith; Patrick-Julian Mester
Journal:  Viruses       Date:  2019-05-22       Impact factor: 5.048

5.  Virucidal activity of a new hand disinfectant with reduced ethanol content: comparison with other alcohol-based formulations.

Authors:  A Kramer; A S Galabov; S A Sattar; L Döhner; A Pivert; C Payan; M H Wolff; A Yilmaz; J Steinmann
Journal:  J Hosp Infect       Date:  2005-11-22       Impact factor: 3.926

6. 

Authors:  I Schwebke; M Eggers; J Gebel; B Geisel; D Glebe; I Rapp; J Steinmann; F Rabenau
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2017-03       Impact factor: 1.513

Review 7.  Bactericidal and virucidal activity of ethanol and povidone-iodine.

Authors:  Andreas Sauerbrei
Journal:  Microbiologyopen       Date:  2020-06-22       Impact factor: 3.139

Review 8.  Hygienic hand antiseptics: should they not have activity and label claims against viruses?

Authors:  Syed A Sattar; V Susan Springthorpe; Jason Tetro; Robert Vashon; Bruce Keswick
Journal:  Am J Infect Control       Date:  2002-10       Impact factor: 2.918

Review 9.  Efficacy of ethanol against viruses in hand disinfection.

Authors:  G Kampf
Journal:  J Hosp Infect       Date:  2017-09-05       Impact factor: 3.926
  9 in total

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