Literature DB >> 11757817

Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice.

S O Mueller1, K S Korach.   

Abstract

The estrogen receptors ERalpha and ERbeta are the main mediators of estrogen action and estrogens play an important role in a variety of aspects of physiology besides their well acknowledged function in reproduction. In vivo and in vitro studies indicate that the estrogen receptors are mechanistically implicated in endocrine-related diseases. Recent studies with estrogen receptor knockout mice have helped to unravel the role of the estrogen receptors in brain degeneration, osteoporosis, cardiovascular diseases and obesity.

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Year:  2001        PMID： 11757817     DOI： 10.1016/s1471-4892(01)00105-9

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN： 1471-4892            Impact factor:   5.547


  26 in total

1.  Fibroblast ERα promotes bladder cancer invasion via increasing the CCL1 and IL-6 signals in the tumor microenvironment.

Authors:  Chiuan-Ren Yeh; Iawen Hsu; Wenbin Song; Hongchiang Chang; Hiroshi Miyamoto; Guang-Qian Xiao; Lei Li; Shuyuan Yeh
Journal:  Am J Cancer Res       Date:  2015-02-15       Impact factor: 6.166

Review 2.  Bone development in the fetus and neonate: role of the calciotropic hormones.

Authors:  Christopher S Kovacs
Journal:  Curr Osteoporos Rep       Date:  2011-12       Impact factor: 5.096

3.  Estrogen sulfotransferase/SULT1E1 promotes human adipogenesis.

Authors:  Chibueze A Ihunnah; Taira Wada; Brian J Philips; Sudheer K Ravuri; Robert B Gibbs; Levent Kirisci; J Peter Rubin; Kacey G Marra; Wen Xie
Journal:  Mol Cell Biol       Date:  2014-02-24       Impact factor: 4.272

4.  An estrogen receptor alpha activity indicator model in mice.

Authors:  Sang Jun Han; Bert W O'Malley; Francesco J DeMayo
Journal:  Genesis       Date:  2009-12       Impact factor: 2.487

5.  Estrogen action and prostate cancer.

Authors:  Jason L Nelles; Wen-Yang Hu; Gail S Prins
Journal:  Expert Rev Endocrinol Metab       Date:  2011-05

6.  Predictive Modeling of Estrogen Receptor Binding Agents Using Advanced Cheminformatics Tools and Massive Public Data.

Authors:  Kathryn Ribay; Marlene T Kim; Wenyi Wang; Daniel Pinolini; Hao Zhu
Journal:  Front Environ Sci       Date:  2016-03-08

7.  Thiophene-core estrogen receptor ligands having superagonist activity.

Authors:  Jian Min; Pengcheng Wang; Sathish Srinivasan; Jerome C Nwachukwu; Pu Guo; Minjian Huang; Kathryn E Carlson; John A Katzenellenbogen; Kendall W Nettles; Hai-Bing Zhou
Journal:  J Med Chem       Date:  2013-04-15       Impact factor: 7.446

Review 8.  Recent experimental and clinical findings in the skeleton associated with loss of estrogen hormone or estrogen receptor activity.

Authors:  Eric P Smith; Bonny Specker; Kenneth S Korach
Journal:  J Steroid Biochem Mol Biol       Date:  2009-11-10       Impact factor: 4.292

9.  Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches.

Authors:  Liying Zhang; Alexander Sedykh; Ashutosh Tripathi; Hao Zhu; Antreas Afantitis; Varnavas D Mouchlis; Georgia Melagraki; Ivan Rusyn; Alexander Tropsha
Journal:  Toxicol Appl Pharmacol       Date:  2013-05-23       Impact factor: 4.219

10.  Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer.

Authors:  Kakoli Das; David Tai Leong; Anurag Gupta; Liang Shen; Thomas Putti; Gary S Stein; Andre J van Wijnen; Manuel Salto-Tellez
Journal:  Eur J Cancer       Date:  2009-07-24       Impact factor: 9.162
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