| Literature DB >> 11755332 |
Mercedes Martín-Martínez1, Miriam Latorre, M Teresa García-López, Edurne Cenarruzabeitia, Joaquín Del Río, Rosario González-Muñiz.
Abstract
Replacement of the 2-Adoc-D-alphaMeTrp residue in the non-selective CCK(1) receptor agonist PD 170292 by the Z-(2R,5R,11bS)-IBTM skeleton, able to fix a type II beta-turn-like conformation, led to a conformationally restricted dipeptoid analogue, namely 3a, which exhibited a notable increase in the CCK(1) selectivity and antagonist properties.Entities:
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Year: 2002 PMID： 11755332 DOI： 10.1016/s0960-894x(01)00630-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823