Literature DB >> 11754618

Four new bioactive pyrrole-derived alkaloids from the marine sponge Axinella brevistyla.

S Tsukamoto1, K Tane, T Ohta, S Matsunaga, N Fusetani, R W van Soest.   

Abstract

Four new alkaloids (1-4) were isolated from the marine sponge Axinella brevistyla, and their structures were determined on the basis of spectroscopic analysis. The alkaloids 1-4 were antifungal against the yeast Saccharomyces cerevisiae at <1.0, <1.0, 30, and 100 microg/disk, respectively. Compounds 1-3 also exhibited cytotoxicity against L1210 cells with IC(50) values of 1.1, 0.66, and 2.5 microg/mL, respectively.

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Year:  2001        PMID： 11754618     DOI： 10.1021/np010280b

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Synthesis of 1-(4-trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles via chain heterocyclization.

Authors:  Mykhaylo V Vovk; Oleksandr M Pinchuk; Andrij O Tolmachov; Andrei A Gakh
Journal:  Molecules       Date:  2010-02-23       Impact factor: 4.411

Review 2.  Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids.

Authors:  Ali Al-Mourabit; Manuel A Zancanella; Supriya Tilvi; Daniel Romo
Journal:  Nat Prod Rep       Date:  2011-05-09       Impact factor: 13.423

3.  Two new pyrrolo-2-aminoimidazoles from a Myanmarese marine sponge, Clathria prolifera.

Authors:  So-Yeun Woo; Nwet Nwet Win; Chin Piow Wong; Takuya Ito; Shotaro Hoshino; Hla Ngwe; Aung Aung Aye; Nang Mya Han; Huiping Zhang; Fumiaki Hayashi; Ikuro Abe; Hiroyuki Morita
Journal:  J Nat Med       Date:  2018-03-22       Impact factor: 2.343

Review 4.  Recent N-atom containing compounds from indo-pacific invertebrates.

Authors:  Yoel Kashman; Ashgan Bishara; Maurice Aknin
Journal:  Mar Drugs       Date:  2010-11-10       Impact factor: 5.118

Review 5.  Marine Pyrrole Alkaloids.

Authors:  Kevin Seipp; Leander Geske; Till Opatz
Journal:  Mar Drugs       Date:  2021-09-10       Impact factor: 5.118

6.  Ethyl 4-(2-chloro-quinolin-3-yl)-1-phenyl-1H-pyrrole-3-carboxyl-ate.

Authors:  Saida Benzerka; Abdelmalek Bouraiou; Sofiane Bouacida; Abdelmadjid Debache; Ali Belfaitah
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-10-15

7.  Bromopyrrole Alkaloids with the Inhibitory Effects against the Biofilm Formation of Gram Negative Bacteria.

Authors:  Jingyuan Sun; Jiru Wu; Bang An; Nicole J de Voogd; Wei Cheng; Wenhan Lin
Journal:  Mar Drugs       Date:  2018-01-02       Impact factor: 5.118

8.  Inhibitory Effects of Nitrogenous Metabolites from a Marine-Derived Streptomyces bacillaris on Isocitrate Lyase of Candida albicans.

Authors:  Beomkoo Chung; Ji-Yeon Hwang; Sung Chul Park; Oh-Seok Kwon; Eunji Cho; Jayho Lee; Hyi-Seung Lee; Dong-Chan Oh; Jongheon Shin; Ki-Bong Oh
Journal:  Mar Drugs       Date:  2022-02-13       Impact factor: 5.118

9.  Neopetrocyclamines A and B, polycyclic diamine alkaloids from the sponge Neopetrosia cf exigua.

Authors:  Zhibin Liang; Florian J Sulzmaier; Wesley Y Yoshida; Michelle Kelly; Joe W Ramos; Philip G Williams
Journal:  J Nat Prod       Date:  2015-01-13       Impact factor: 4.803

10.  Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji-Trost coupling.

Authors:  Sebastian Bretzke; Stephan Scheeff; Felicitas Vollmeyer; Friederike Eberhagen; Frank Rominger; Dirk Menche
Journal:  Beilstein J Org Chem       Date:  2016-06-02       Impact factor: 2.883
  10 in total

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