Literature DB >> 11754610

New sesquiterpene derivatives from the red alga Laurencia scoparia. Isolation, structure determination, and anthelmintic activity.

D Davyt1, R Fernandez, L Suescun, A W Mombrú, J Saldaña, L Domínguez, J Coll, M T Fujii, E Manta.   

Abstract

Eleven sesquiterpenes (1-11) and one long chain aldehyde (12) have been isolated from the dichloromethane extract of the red alga Laurencia scoparia. Four of them are new natural products. Scopariol (1) is a new natural product with an unusual rearranged chamigrane-type structure. The other three are beta-chamigrenes: isorigidol (2), (+)-3-(Z)-bromomethylidene-10 beta-bromo-beta-chamigrene (3), and (-)-3-(E)-bromomethylidene-10 beta-bromo-beta-chamigrene (4). The in vitro activity of compounds 1-12 against the parasitant stage of Nippostrongylus brasiliensis (L4) has been studied.

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Year:  2001        PMID： 11754610     DOI： 10.1021/np0102307

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  A Unified Approach for the Enantioselective Synthesis of the Brominated Chamigrene Sesquiterpenes.

Authors:  Alexander J Burckle; Vasil H Vasilev; Noah Z Burns
Journal:  Angew Chem Int Ed Engl       Date:  2016-08-10       Impact factor: 15.336

2.  Enantioselective synthesis of (+)-majusculone.

Authors:  Douglass F Taber; M Inthikhab Sikkander; Pierre H Storck
Journal:  J Org Chem       Date:  2007-04-21       Impact factor: 4.354

3.  Cytotoxic compounds from Laurencia pacifica.

Authors:  Diana A Zaleta-Pinet; Ian P Holland; Mauricio Muñoz-Ochoa; J Ivan Murillo-Alvarez; Jennette A Sakoff; Ian A van Altena; Adam McCluskey
Journal:  Org Med Chem Lett       Date:  2014-09-20

4.  The Prospective Use of Brazilian Marine Macroalgae in Schistosomiasis Control.

Authors:  Erika M Stein; Sara G Tajú; Patrícia A Miyasato; Rafaela P de Freitas; Lenita de F Tallarico; Guilherme S Dos Santos; Giovana L F Luiz; Henrique K Rofatto; Fábio N V da Silva; Pio Colepicolo; Arthur L Macedo; Carlos A Carollo; Eliana Nakano
Journal:  Mar Drugs       Date:  2021-04-22       Impact factor: 5.118

Review 5.  Halogenated compounds from marine algae.

Authors:  Maria Teresa Cabrita; Carlos Vale; Amélia Pilar Rauter
Journal:  Mar Drugs       Date:  2010-08-09       Impact factor: 5.118

6.  Nitric Oxide Production Inhibition and Anti-Mycobacterial Activity of Extracts and Halogenated Sesquiterpenes from the Brazilian Red Alga Laurencia Dendroidea J. Agardh.

Authors:  Thatiana Lopes Biá Ventura; Fernanda Lacerda da Silva Machado; Marlon Heggdorne de Araujo; Lísia Mônica de Souza Gestinari; Carlos Roland Kaiser; Francisco de Assis Esteves; Elena B Lasunskaia; Angélica Ribeiro Soares; Michelle Frazão Muzitano
Journal:  Pharmacogn Mag       Date:  2015-10       Impact factor: 1.085

7.  Effect of Rhodophyta extracts on in vitro ruminal fermentation characteristics, methanogenesis and microbial populations.

Authors:  Shin Ja Lee; Nyeon Hak Shin; Jin Suk Jeong; Eun Tae Kim; Su Kyoung Lee; Sung Sill Lee
Journal:  Asian-Australas J Anim Sci       Date:  2017-12-21       Impact factor: 2.509

8.  Isolaurenidificin and Bromlaurenidificin, Two New C15-Acetogenins from the Red Alga Laurencia obtusa.

Authors:  Nahed O Bawakid; Walied M Alarif; Najla A Alburae; Hajer S Alorfi; Khalid O Al-Footy; Sultan S Al-Lihaibi; Mohamed A Ghandourah
Journal:  Molecules       Date:  2017-05-15       Impact factor: 4.411

9.  Chamigrane Sesquiterpenes from a Basidiomycetous Endophytic Fungus XG8D Associated with Thai Mangrove Xylocarpus granatum.

Authors:  Siwattra Choodej; Thapong Teerawatananond; Tohru Mitsunaga; Khanitha Pudhom
Journal:  Mar Drugs       Date:  2016-07-15       Impact factor: 5.118

10.  Sesquiterpenes from Laurencia similis.

Authors:  Hua Su; Da-Yong Shi; Jing Li; Shu-Ju Guo; Li-Li Li; Zhao-Hui Yuan; Xiao-Bin Zhu
Journal:  Molecules       Date:  2009-05-20       Impact factor: 4.411
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