Literature DB >> 11753213

CD14 and LBP in endotoxemia and infections caused by Gram-negative bacteria.

D Heumann1.   

Abstract

It is now well recognized that plasma LPS-binding protein (LBP) and membrane CD14 present at the surface of cells of the myelo/monocytic lineage are central molecules of the innate immune system, in response to LPS or to bacterial products. This paper reviews the role of LBP and CD14 in models of endotoxemia and infection.

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Year:  2001        PMID: 11753213

Source DB:  PubMed          Journal:  J Endotoxin Res        ISSN: 0968-0519


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