Literature DB >> 11752281

PharmGKB: the Pharmacogenetics Knowledge Base.

Micheal Hewett1, Diane E Oliver, Daniel L Rubin, Katrina L Easton, Joshua M Stuart, Russ B Altman, Teri E Klein.   

Abstract

The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.

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Year:  2002        PMID： 11752281      PMCID： PMC99138          DOI： 10.1093/nar/30.1.163

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  6 in total

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