Literature DB >> 11748209

Influence of the length of the lipooligosaccharide alpha chain on its sialylation in Neisseria meningitidis.

Chao-Ming Tsai1, George Kao, Peixuan Zhu.   

Abstract

The sialylation of lipooligosaccharide (LOS) in Neisseria meningitidis plays a role in the resistance of the organism to killing by normal human serum. The length of the alpha chain extending out from the heptose I [Hep (I)] moiety of LOS influenced sialylation of N. meningitidis LOS in vitro and in vivo. The alpha chain required a terminal Gal and a trisaccharide or longer oligosaccharide to serve as an acceptor for sialylation. The disaccharide lactose (Galbeta1-4Glc) in the alpha chain of immunotype L8 LOS could not function as an acceptor for the sialyltransferase, probably due to steric hindrance imposed by the neighboring Hep (II) with phosphorylethanolamine and another group attached.

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Year:  2002        PMID： 11748209      PMCID： PMC127647          DOI： 10.1128/IAI.70.1.407-411.2002

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  30 in total

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Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

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Journal:  Anal Biochem       Date:  1982-01-01       Impact factor: 3.365

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Journal:  Nature       Date:  1970-07-25       Impact factor: 49.962

7.  Sialylation of lipopolysaccharide and loss of absorption of bactericidal antibody during conversion of gonococci to serum resistance by cytidine 5'-monophospho-N-acetyl neuraminic acid.

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Journal:  Microb Pathog       Date:  1989-07       Impact factor: 3.738

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Journal:  J Biol Chem       Date:  1987-02-05       Impact factor: 5.157

Review 9.  Molecular mimicry of host structures by lipooligosaccharides of Neisseria meningitidis: characterization of sialylated and nonsialylated lacto-N-neotetraose (Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc) structures in lipooligosaccharides using monoclonal antibodies and specific lectins.

Authors:  C M Tsai
Journal:  Adv Exp Med Biol       Date:  2001       Impact factor: 2.622

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Authors:  C M Tsai; R Boykins; C E Frasch
Journal:  J Bacteriol       Date:  1983-08       Impact factor: 3.490
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  6 in total

1.  Differential expression and transcriptional analysis of the alpha-2,3-sialyltransferase gene in pathogenic Neisseria spp.

Authors:  Mathanraj Packiam; Dawn M Shell; Shi V Liu; Yao-Bin Liu; David J McGee; Ranjana Srivastava; Samar Seal; Richard F Rest
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

2.  Genetic and structural characterization of L11 lipooligosaccharide from Neisseria meningitidis serogroup A strains.

Authors:  Noëlle Mistretta; Delphine Seguin; Jerôme Thiébaud; Sandrine Vialle; Frédéric Blanc; Marina Brossaud; Philippe Talaga; Gunnstein Norheim; Monique Moreau; Bachra Rokbi
Journal:  J Biol Chem       Date:  2010-04-26       Impact factor: 5.157

3.  Lipooligosaccharide Structures of Invasive and Carrier Isolates of Neisseria meningitidis Are Correlated with Pathogenicity and Carriage.

Authors:  Constance M John; Nancy J Phillips; Richard Din; Mingfeng Liu; Einar Rosenqvist; E Arne Høiby; Daniel C Stein; Gary A Jarvis
Journal:  J Biol Chem       Date:  2015-12-11       Impact factor: 5.157

4.  Activation of toll-like receptor 2 (TLR2) and TLR4/MD2 by Neisseria is independent of capsule and lipooligosaccharide (LOS) sialylation but varies widely among LOS from different strains.

Authors:  Alison C Pridmore; Gary A Jarvis; Constance M John; Dominic L Jack; Steven K Dower; Robert C Read
Journal:  Infect Immun       Date:  2003-07       Impact factor: 3.441

5.  Profiles of structural heterogeneity in native lipooligosaccharides of Neisseria and cytokine induction.

Authors:  Constance M John; Mingfeng Liu; Gary A Jarvis
Journal:  J Lipid Res       Date:  2008-10-02       Impact factor: 5.922

Review 6.  Sweet impersonators: Molecular mimicry of host glycans by bacteria.

Authors:  Hanna de Jong; Marc M S M Wösten; Tom Wennekes
Journal:  Glycobiology       Date:  2022-02-26       Impact factor: 4.313
  6 in total

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