Literature DB >> 11738420

Alkaloids from Cynanchum komarovii with inhibitory activity against the tobacco mosaic virus.

T An1, R Q Huang, Z Yang, D K Zhang, G R Li, Y C Yao, J Gao.   

Abstract

A pyrroloisoquinoline alkaloid, 2,3-dimethoxy-6-(3-oxo-butyl)-7,9,10,11,11a,12-hexahydrobenzo[f]pyrrolo[1,2-b]isoquinoline (1), whose structure was determined by spectroscopic methods, was isolated from the aerial parts of Cynanchum komarovii, together with two known alkaloids, 7-demethoxytylophorine (2) and 7-demethoxytylophorine N-oxide (3). Alkaloids 2 and 3 had antiviral activities against tobacco mosaic virus.

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Year:  2001        PMID： 11738420     DOI： 10.1016/s0031-9422(01)00382-x

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  11 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-30       Impact factor: 11.205

3.  Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of glycoconjugates of phenanthroindolizidines alkaloids.

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4.  Effects of the Papaya meleira virus on papaya latex structure and composition.

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5.  Discovery and SARs of trans-3-aryl acrylic acids and their analogs as novel anti-tobacco mosaic virus (TMV) agents.

Authors:  Meng Wu; Ziwen Wang; Chuisong Meng; Kailiang Wang; Yanna Hu; Lizhong Wang; Qingmin Wang
Journal:  PLoS One       Date:  2013-02-13       Impact factor: 3.240

6.  Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents.

Authors:  Haining Lv; Jinhong Ren; Shuanggang Ma; Song Xu; Jing Qu; Zhenjia Liu; Qing Zhou; Xiaoguang Chen; Shishan Yu
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Review 7.  Possible pharmaceutical applications can be developed from naturally occurring phenanthroindolizidine and phenanthroquinolizidine alkaloids.

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Journal:  Phytochem Rev       Date:  2020-09-25       Impact factor: 7.741

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9.  First discovery and stucture-activity relationship study of phenanthroquinolizidines as novel antiviral agents against tobacco mosaic virus (TMV).

Authors:  Ziwen Wang; Anzheng Feng; Mingbo Cui; Yuxiu Liu; Lizhong Wang; Qingmin Wang
Journal:  PLoS One       Date:  2012-12-28       Impact factor: 3.240

Review 10.  Ethnobotany, Phytochemistry and Pharmacological Effects of Plants in Genus Cynanchum Linn. (Asclepiadaceae).

Authors:  Lu Han; Xiuping Zhou; Mengmeng Yang; Li Zhou; Xinxin Deng; Shijie Wei; Wenping Wang; Zhizhong Wang; Xue Qiao; Changcai Bai
Journal:  Molecules       Date:  2018-05-16       Impact factor: 4.411
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