Literature DB >> 11738401

Taxines from the needles of Taxus wallichiana.

J K Prasain1, P Stefanowicz, T Kiyota, F Habeichi, Y Konishi.   

Abstract

A taxine, 5 alpha O-(3'-dimethylamino-3'-phenylpropionyl) taxinine M (1) together with two known compounds 7-O-acetyltaxine A (2) and 2 alpha-acetoxy-2' beta-deacetylaustrospicatine (3) were isolated from the needles of the Himalayan yew, Taxus wallichiana Zucc. Their structures were elucidated on the basis of the NMR spectral data, ESI-MS/MS analysis and chemical methods. Compounds 1 and 3 showed moderate cytotoxic activity against the lung cancer cell line A549 in vitro.

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Year:  2001        PMID： 11738401     DOI： 10.1016/s0031-9422(01)00305-3

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  7 in total

1.  Cytotoxicity of hydro-alcoholic extracts of Cucurbitapepo and Solanum nigrum on HepG2 and CT26 cancer cell lines.

Authors:  M Shokrzadeh; M Azadbakht; N Ahangar; A Hashemi; S S Saeedi Saravi
Journal:  Pharmacogn Mag       Date:  2010-07       Impact factor: 1.085

2.  Comparison of the cytotoxic effects of Juniperus sabina and Zataria multiflora extracts with Taxus baccata extract and Cisplatin on normal and cancer cell lines.

Authors:  M Shokrzadeh; M Azadbakht; N Ahangar; H Naderi; S S Saeedi Saravi
Journal:  Pharmacogn Mag       Date:  2010-05-05       Impact factor: 1.085

3.  Cytotoxic and growth inhibitory effects of the methanol extract Struchium sparganophora Ktze (Asteraceae) leaves.

Authors:  B A Ayinde; U Agbakwuru
Journal:  Pharmacogn Mag       Date:  2010-10       Impact factor: 1.085

4.  Absolute configuration of (2S)-4-(4-hy-droxy-phen-yl)butan-2-ol.

Authors:  S Yousuf; S G Musharraf; I Khan; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-03-23

Review 5.  Discovery and resupply of pharmacologically active plant-derived natural products: A review.

Authors:  Atanas G Atanasov; Birgit Waltenberger; Eva-Maria Pferschy-Wenzig; Thomas Linder; Christoph Wawrosch; Pavel Uhrin; Veronika Temml; Limei Wang; Stefan Schwaiger; Elke H Heiss; Judith M Rollinger; Daniela Schuster; Johannes M Breuss; Valery Bochkov; Marko D Mihovilovic; Brigitte Kopp; Rudolf Bauer; Verena M Dirsch; Hermann Stuppner
Journal:  Biotechnol Adv       Date:  2015-08-15       Impact factor: 14.227

Review 6.  Taxanes and taxoids of the genus Taxus - A comprehensive inventory of chemical diversity.

Authors:  B Markus Lange; Caleb F Conner
Journal:  Phytochemistry       Date:  2021-07-27       Impact factor: 4.004

Review 7.  Ethnomedical properties of taxus wallichiana zucc. (Himalayan yew).

Authors:  Deepak Juyal; Vijay Thawani; Shweta Thaledi; Manoj Joshi
Journal:  J Tradit Complement Med       Date:  2014-07
  7 in total

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