| Literature DB >> 11731917 |
L Muschietti1, S Gorzalczany, G Ferraro, C Acevedo, V Martino.
Abstract
Anti-inflammatory activity was detected in the CH(2)Cl(2) extract of the aerial parts of Eupatorium buniifolium using the TPA-mouse ear model. Three compounds isolated from this extract, by bioassay-guided fractionation, significantly inhibited the inflammatory response. The compounds were identified as 5,7,5'-trihydroxy-3,6,2',4'-tetramethoxyflavone (1), scopoletin (2) and centaureidin (3) which inhibited the edema by 67.3 %, 59.8 % and 49.7 %, respectively, at a dose of 1 mg/ear.Entities:
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Year: 2001 PMID： 11731917 DOI： 10.1055/s-2001-18355
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352