Literature DB >> 11731115

Effect of Spirulina fusiformis on cyclophosphamide and mitomycin-C induced genotoxicity and oxidative stress in mice.

K Premkumar1, A Pachiappan, S K Abraham, S T Santhiya, P M Gopinath, A Ramesh.   

Abstract

Spirulina fusiformis was tested for its possible in vivo protective effects against cyclophosphamide (CP) and mitomycin-C (MMC) induced genotoxicity and oxidative stress in mice. Pre-treatment with S. fusiformis (250, 500 and 1000 mg kg(-1), p.o., daily for 5 days) significantly reduced the chromosomal damage and lipid peroxidation with concomitant changes in antioxidants and detoxification systems. All the three tested doses were effective in exerting a protective effect against CP and MMC.

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Year:  2001        PMID： 11731115     DOI： 10.1016/s0367-326x(01)00340-9

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  12 in total

1.  The protective effect of dietary Arthrospira (Spirulina) maxima against mutagenicity induced by benzo[alpha]pyrene in mice.

Authors:  Germán Chamorro-Cevallos; Leticia Garduño-Siciliano; Elizdath Martínez-Galero; Angélica Mojica-Villegas; Nicole Pages; Gabriela Gutiérrez-Salmeán
Journal:  J Med Food       Date:  2014-05-02       Impact factor: 2.786

2.  The impact of several hydraulic fracking chemicals on Nile tilapia and evaluation of the protective effects of Spirulina platensis.

Authors:  Mahmoud A Mahmoud; Abeer H Abd El-Rahim; Karima F Mahrous; Mohamed Abdelsalam; Nashwa A Abu-Aita; Mamdouh Afify
Journal:  Environ Sci Pollut Res Int       Date:  2019-05-10       Impact factor: 4.223

3.  Neuroprotective effect of Spirulina in cerebral ischemia-reperfusion injury in rats.

Authors:  Santhrani Thaakur; Ravi Sravanthi
Journal:  J Neural Transm (Vienna)       Date:  2010-08-11       Impact factor: 3.575

4.  Protective effect of centella triterpene saponins against cyclophosphamide-induced immune and hepatic system dysfunction in rats: its possible mechanisms of action.

Authors:  Pragathi Duggina; Chandra Mouli Kalla; Seshadri Reddy Varikasuvu; Suman Bukke; Vijaya Tartte
Journal:  J Physiol Biochem       Date:  2015-07-14       Impact factor: 4.158

Review 5.  Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.

Authors:  Ruitang Deng; Te-Jin Chow
Journal:  Cardiovasc Ther       Date:  2010-08       Impact factor: 3.023

6.  Appraisal of immunomodulatory potential of Spirulina fusiformis: an in vivo and in vitro study.

Authors:  Mahaboobkhan Rasool; Evan Prince Sabina
Journal:  J Nat Med       Date:  2008-12-18       Impact factor: 2.343

7.  Behavioral and Histopathological Study of Changes in Spinal Cord Injured Rats Supplemented with Spirulina platensis.

Authors:  Izzuddin Aziz; Muhammad Danial Che Ramli; Nurul Suraya Mohd Zain; Junedah Sanusi
Journal:  Evid Based Complement Alternat Med       Date:  2014-07-24       Impact factor: 2.629

8.  Dioscorea bulbifera polysaccharide and cyclophosphamide combination enhances anti-cervical cancer effect and attenuates immunosuppression and oxidative stress in mice.

Authors:  Hongxia Cui; Ting Li; Liping Wang; Yan Su; Cory J Xian
Journal:  Sci Rep       Date:  2016-01-12       Impact factor: 4.379

9.  Ameliorative Effect of Caffeic Acid on Capecitabine-Induced Hepatic and Renal Dysfunction: Involvement of the Antioxidant Defence System.

Authors:  Ebenezer Tunde Olayinka; Olaniyi Solomon Ola; Ayokanmi Ore; Oluwatobi Adewumi Adeyemo
Journal:  Medicines (Basel)       Date:  2017-10-25

10.  Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis.

Authors:  Wing Pak; Fusako Takayama; Manaka Mine; Kazuo Nakamoto; Yasumasa Kodo; Mitsumasa Mankura; Toru Egashira; Hiromu Kawasaki; Akitane Mori
Journal:  J Clin Biochem Nutr       Date:  2012-10-12       Impact factor: 3.114
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