Literature DB >> 11719114

Isolation of mitochondria from Plasmodium falciparum showing dihydroorotate dependent respiration.

E Takashima1, S Takamiya, S Takeo, F Mi-ichi, H Amino, K Kita.   

Abstract

Using N2 cavitation, we established a protocol to prepare the active mitochondria from Plasmodium falciparum showing a higher succinate dehydrogenase activity than previously reported and a dihydroorotate-dependent respiration. The fact that fumarate partially inhibited the dihydroorotate dependent respiration suggests that complex II (succinate-ubiquinone reductase/quinol-fumarate reductase) in the erythrocytic stage cells of P. falciparum functions as a quinol-fumarate reductase.

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Year:  2001        PMID： 11719114     DOI： 10.1016/s1383-5769(01)00085-x

Source DB:  PubMed          Journal:  Parasitol Int        ISSN： 1383-5769            Impact factor:   2.230


  10 in total

1.  Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle.

Authors:  Hangjun Ke; Ian A Lewis; Joanne M Morrisey; Kyle J McLean; Suresh M Ganesan; Heather J Painter; Michael W Mather; Marcelo Jacobs-Lorena; Manuel Llinás; Akhil B Vaidya
Journal:  Cell Rep       Date:  2015-04-02       Impact factor: 9.423

2.  Hemozoin-free Plasmodium falciparum mitochondria for physiological and drug susceptibility studies.

Authors:  Michael W Mather; Joanne M Morrisey; Akhil B Vaidya
Journal:  Mol Biochem Parasitol       Date:  2010-07-30       Impact factor: 1.759

3.  A Novel Methodology for Bioenergetic Analysis of Plasmodium falciparum Reveals a Glucose-Regulated Metabolic Shift and Enables Mode of Action Analyses of Mitochondrial Inhibitors.

Authors:  Tomoyo Sakata-Kato; Dyann F Wirth
Journal:  ACS Infect Dis       Date:  2016-10-25       Impact factor: 5.084

4.  Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Authors:  Kellen L Olszewski; Michael W Mather; Joanne M Morrisey; Benjamin A Garcia; Akhil B Vaidya; Joshua D Rabinowitz; Manuel Llinás
Journal:  Nature       Date:  2010-08-05       Impact factor: 49.962

5.  A drug-selected Plasmodium falciparum lacking the need for conventional electron transport.

Authors:  Martin J Smilkstein; Isaac Forquer; Atsuko Kanazawa; Jane Xu Kelly; Rolf W Winter; David J Hinrichs; David M Kramer; Michael K Riscoe
Journal:  Mol Biochem Parasitol       Date:  2008-01-19       Impact factor: 1.759

6.  Novel Characteristics of Mitochondrial Electron Transport Chain from Eimeria tenella.

Authors:  Makoto Matsubayashi; Daniel Ken Inaoka; Keisuke Komatsuya; Takeshi Hatta; Fumiya Kawahara; Kimitoshi Sakamoto; Kenji Hikosaka; Junya Yamagishi; Kazumi Sasai; Tomoo Shiba; Shigeharu Harada; Naotoshi Tsuji; Kiyoshi Kita
Journal:  Genes (Basel)       Date:  2019-01-08       Impact factor: 4.096

7.  Siccanin Is a Dual-Target Inhibitor of Plasmodium falciparum Mitochondrial Complex II and Complex III.

Authors:  Keisuke Komatsuya; Takaya Sakura; Kazuro Shiomi; Satoshi Ōmura; Kenji Hikosaka; Tomoyoshi Nozaki; Kiyoshi Kita; Daniel Ken Inaoka
Journal:  Pharmaceuticals (Basel)       Date:  2022-07-21

8.  Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection.

Authors:  Keith Kiplangat Talaam; Daniel Ken Inaoka; Takeshi Hatta; Daigo Tsubokawa; Naotoshi Tsuji; Minoru Wada; Hiroyuki Saimoto; Kiyoshi Kita; Shinjiro Hamano
Journal:  Antimicrob Agents Chemother       Date:  2021-08-02       Impact factor: 5.191

Review 9.  Mitochondria in malaria and related parasites: ancient, diverse and streamlined.

Authors:  Michael W Mather; Akhil B Vaidya
Journal:  J Bioenerg Biomembr       Date:  2008-09-24       Impact factor: 3.853

10.  Identification of clustered organellar short (cos) RNAs and of a conserved family of organellar RNA-binding proteins, the heptatricopeptide repeat proteins, in the malaria parasite.

Authors:  Arne Hillebrand; Joachim M Matz; Martin Almendinger; Katja Müller; Kai Matuschewski; Christian Schmitz-Linneweber
Journal:  Nucleic Acids Res       Date:  2018-11-02       Impact factor: 16.971
  10 in total

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