Literature DB >> 11713313

REPuter: the manifold applications of repeat analysis on a genomic scale.

S Kurtz1, J V Choudhuri, E Ohlebusch, C Schleiermacher, J Stoye, R Giegerich.   

Abstract

The repetitive structure of genomic DNA holds many secrets to be discovered. A systematic study of repetitive DNA on a genomic or inter-genomic scale requires extensive algorithmic support. The REPuter program described herein was designed to serve as a fundamental tool in such studies. Efficient and complete detection of various types of repeats is provided together with an evaluation of significance and interactive visualization. This article circumscribes the wide scope of repeat analysis using applications in five different areas of sequence analysis: checking fragment assemblies, searching for low copy repeats, finding unique sequences, comparing gene structures and mapping of cDNA/EST sequences.

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Year:  2001        PMID： 11713313      PMCID： PMC92531          DOI： 10.1093/nar/29.22.4633

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  17 in total

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Authors:  S Kurtz; C Schleiermacher
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Journal:  Nature       Date:  2001-02-15       Impact factor: 49.962

5.  The REPRO server: finding protein internal sequence repeats through the Web.

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Journal:  Trends Biochem Sci       Date:  2000-10       Impact factor: 13.807

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