| Literature DB >> 11707593 |
D Kaplan1, D Smith, H Meyerson, N Pecora, K Lewandowska.
Abstract
Dim expression of CD5 on human B lymphocytes has been used to delineate B1 and B2 subsets. Nevertheless, others have suggested that the molecule is an activation marker and does not predicate a subset distinction. We have used enzymatic amplification staining, a technology that enhances the resolution of flow cytometric analysis of cell surface molecules by as much as 100-fold, to determine that essentially all human B cells express CD5. Furthermore, we show that this expression is regulated during Epstein-Barr virus transformation.Entities:
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Year: 2001 PMID： 11707593 PMCID： PMC61130 DOI： 10.1073/pnas.241509398
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205