Literature DB >> 1170491

The mechanism of action of methotrexate. III. Requirement of free intracellular methotrexate for maximal suppression of (14C)formate incorporation into nucleic acids and protein.

J C White, S Loftfield, I D Goldman.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1170491

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


× No keyword cloud information.
  12 in total

1.  Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme.

Authors:  C K Barlowe; D R Appling
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

Review 2.  Polyglutamation of methotrexate. Is methotrexate a prodrug?

Authors:  B A Chabner; C J Allegra; G A Curt; N J Clendeninn; J Baram; S Koizumi; J C Drake; J Jolivet
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

3.  Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.

Authors:  John T Cunningham; Melissa V Moreno; Alessia Lodi; Sabrina M Ronen; Davide Ruggero
Journal:  Cell       Date:  2014-05-22       Impact factor: 41.582

4.  Use of the circuit simulation program SPICE2 for analysis of the metabolism of anticancer drugs.

Authors:  J C White
Journal:  Bull Math Biol       Date:  1986       Impact factor: 1.758

Review 5.  Antineoplastic drugs: clinical pharmacology and therapeutic use.

Authors:  R A Bender; L A Zwelling; J H Doroshow; G Y Locker; K R Hande; D S Murinson; M Cohen; C E Myers; B A Chabner
Journal:  Drugs       Date:  1978-07       Impact factor: 9.546

6.  Intra-articular methotrexate. Clinical and laboratory study in rheumatoid and psoriatic arthritis.

Authors:  G H Hall; B J Jones; A C Head; V E Jones
Journal:  Ann Rheum Dis       Date:  1978-08       Impact factor: 19.103

7.  Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.

Authors:  J Jolivet; R L Schilsky; B D Bailey; J C Drake; B A Chabner
Journal:  J Clin Invest       Date:  1982-08       Impact factor: 14.808

8.  The interaction between fluoropyrimidines and methotrexate, and [4C]-formate incorporation into nucleic acids and protein.

Authors:  D Bowen; E Fölsch; L A Guernsey
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

9.  Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates.

Authors:  Adam L VanWert; Douglas H Sweet
Journal:  Pharm Res       Date:  2007-07-28       Impact factor: 4.200

10.  Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.

Authors:  G A Curt; J Jolivet; D N Carney; B D Bailey; J C Drake; N J Clendeninn; B A Chabner
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.