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Literature DB >> 11704889

Association of human herpesvirus 6 and human herpesvirus 7 with demyelinating diseases of the nervous system.

V Tomsone¹, I Logina, A Millers, S Chapenko, S Kozireva, M Murovska.

Abstract

Peripheral blood mononuclear cells and plasma of 113 patients with neurological disorders and 150 blood donors were analyzed for HHV-6 and HHV-7 sequences by PCR. The prevalence of HHV-6 was significantly higher in patients with multiple sclerosis (P < 0.01) than in cases of nondemyelinating diseases of the central and demyelinating diseases of the peripheral nervous systems and blood donors. HHV-6 viremia was found only in patients with multiple sclerosis, predominantly in the active phase of the disease. A significantly higher frequency of HHV-7 reactivation in patients with demyelinating diseases of the peripheral nervous system suggests also its association with demyelinating processes.

Entities: Disease Species

Mesh：

Substances：
DNA, Viral

Year: 2001 PMID： 11704889 DOI： 10.1080/135502801753248150

Source DB: PubMed Journal: J Neurovirol ISSN： 1355-0284 Impact factor: 2.643

37 in total

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12 in total

Review 1. Human herpesvirus 6 infection as a trigger of multiple sclerosis.

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Journal: Mayo Clin Proc Date: 2010-10-06 Impact factor: 7.616

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Authors: Nadia Ben Fredj; Antonella Rotola; Faten Nefzi; Saber Chebel; Roberta Rizzo; Elisabetta Caselli; Mahbouba Frih-Ayed; Dario Di Luca; Mahjoub Aouni
Journal: J Neurovirol Date: 2011-11-05 Impact factor: 2.643

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Authors: Svetlana Chapenko; Silvija Roga; Sandra Skuja; Santa Rasa; Maksims Cistjakovs; Simons Svirskis; Zane Zaserska; Valerija Groma; Modra Murovska
Journal: J Neurovirol Date: 2016-01-04 Impact factor: 2.643

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Journal: J Virol Date: 2016-07-11 Impact factor: 5.103