| Literature DB >> 11701654 |
T Ideker1, T Galitski, L Hood.
Abstract
Systems biology studies biological systems by systematically perturbing them (biologically, genetically, or chemically); monitoring the gene, protein, and informational pathway responses; integrating these data; and ultimately, formulating mathematical models that describe the structure of the system and its response to individual perturbations. The emergence of systems biology is described, as are several examples of specific systems approaches.Mesh：
Year: 2001 PMID： 11701654 DOI： 10.1146/annurev.genom.2.1.343
Source DB: PubMed Journal: Annu Rev Genomics Hum Genet ISSN： 1527-8204 Impact factor: 8.929