Literature DB >> 11694367

Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis.

N Lall1, J J Meyer.   

Abstract

The binaphthoquinoid, diospyrin, was isolated from Euclea natalensis A.DC., and evaluated for its activity against drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. The minimal inhibitory concentration (MIC) of diospyrin was found to be 100 microg/ml for all the M. tuberculosis strains.

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Year:  2001        PMID： 11694367     DOI： 10.1016/s0378-8741(01)00356-7

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  8 in total

1.  Medicinal plants used for the treatment of tuberculosis by Bapedi traditional healers in three districts of the Limpopo Province, South Africa.

Authors:  Sebua Silas Semenya; Alfred Maroyi
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-12-31

2.  The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action.

Authors:  Shantanu Karkare; Terence T H Chung; Frederic Collin; Lesley A Mitchenall; Adam R McKay; Sandra J Greive; Jacobus J M Meyer; Namrita Lall; Anthony Maxwell
Journal:  J Biol Chem       Date:  2012-12-28       Impact factor: 5.157

3.  Phytotherapeutic information on plants used for the treatment of tuberculosis in eastern cape province, South Africa.

Authors:  I O Lawal; D S Grierson; A J Afolayan
Journal:  Evid Based Complement Alternat Med       Date:  2014-04-22       Impact factor: 2.629

Review 4.  Plants in our combating strategies against Mycobacterium tuberculosis: progress made and obstacles met.

Authors:  Vivek Kumar Gupta; M Madhan Kumar; Deepa Bisht; Anupam Kaushik
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

Review 5.  Review of Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of Euclea natalensis A.DC.

Authors:  Alfred Maroyi
Journal:  Molecules       Date:  2017-12-02       Impact factor: 4.411

6.  Global chemical composition and antioxidant and anti-tuberculosis activities of various extracts of Globularia alypum L. (Globulariaceae) leaves.

Authors:  Daycem Khlifi; Moktar Hamdi; Akrem El Hayouni; Sylvie Cazaux; Jean Pierre Souchard; François Couderc; Jalloul Bouajila
Journal:  Molecules       Date:  2011-12-19       Impact factor: 4.411

Review 7.  The potential of plant systems to break the HIV-TB link.

Authors:  Peyman Habibi; Henry Daniell; Carlos Ricardo Soccol; Maria Fatima Grossi-de-Sa
Journal:  Plant Biotechnol J       Date:  2019-07-18       Impact factor: 9.803

8.  Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis.

Authors:  Kamel Djaout; Vinayak Singh; Yap Boum; Victoria Katawera; Hubert F Becker; Natassja G Bush; Stephen J Hearnshaw; Jennifer E Pritchard; Pauline Bourbon; Peter B Madrid; Anthony Maxwell; Valerie Mizrahi; Hannu Myllykallio; Sean Ekins
Journal:  Sci Rep       Date:  2016-06-10       Impact factor: 4.379
  8 in total

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