| Literature DB >> 11687794 |
A T Rovio1, D R Marchington, S Donat, H C Schuppe, J Abel, E Fritsche, D J Elliott, P Laippala, A L Ahola, D McNay, R F Harrison, B Hughes, T Barrett, D M Bailey, D Mehmet, A M Jequier, T B Hargreave, S H Kao, J M Cummins, D E Barton, H J Cooke, Y H Wei, L Wichmann, J Poulton, H T Jacobs.
Abstract
Human mitochondrial DNA polymerase, encoded by POLG, contains a polyglutamine tract encoded by a CAG microsatellite repeat. Analysis of POLG genotypes in different populations identified an association between absence of the common, ten-repeat allele and male infertility typified by a range of sperm quality defects but excluding azoospermia.Entities:
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Year: 2001 PMID： 11687794 DOI： 10.1038/ng759
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330