Literature DB >> 11685056

Treatment of superior limbic keratoconjunctivitis by application of autologous serum.

E Goto1, S Shimmura, J Shimazaki, K Tsubota.   

Abstract

PURPOSE: To determine the efficacy of autologous serum drops in the treatment of superior limbic keratoconjunctivitis (SLK).
METHODS: Twenty-two eyes of 11 patients were diagnosed with SLK. All eyes were treated with 20% diluted autologous serum eyedrops 10 times a day in addition to ongoing treatment of dry eye. Fluorescein and rose bengal staining scores, as well as subjective symptom gradings, were performed before and after 4 weeks of therapy.
RESULTS: Nine of the 11 patients responded well to treatment (82%). The average rose bengal and fluorescein score improved ( p < 0.05), and there was subjective improvement.
CONCLUSION: Autologous serum application can be used as an alternative mode of therapy in SLK.

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Year:  2001        PMID: 11685056     DOI: 10.1097/00003226-200111000-00006

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  32 in total

1.  [Epitheliotrophic capacity of serum and plasma eyedrops. Influence of centrifugation].

Authors:  P Herminghaus; G Geerling; D Hartwig; T Wedel; L Dibbelt
Journal:  Ophthalmologe       Date:  2004-10       Impact factor: 1.059

2.  An optimised protocol for the production of autologous serum eyedrops.

Authors:  L Liu; D Hartwig; S Harloff; P Herminghaus; T Wedel; G Geerling
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-03-09       Impact factor: 3.117

Review 3.  [Albumin eye drops for treatment of ocular surface diseases].

Authors:  J D Unterlauft; M Kohlhaas; I Hofbauer; K Kasper; G Geerling
Journal:  Ophthalmologe       Date:  2009-10       Impact factor: 1.059

Review 4.  Graft failure: II. Ocular surface complications.

Authors:  Samar A Al-Swailem
Journal:  Int Ophthalmol       Date:  2008-06       Impact factor: 2.031

5.  Effect of human autologous serum and fetal bovine serum on human corneal epithelial cell viability, migration and proliferation in vitro.

Authors:  Ming-Feng Wu; Tanja Stachon; Berthold Seitz; Achim Langenbucher; Nóra Szentmáry
Journal:  Int J Ophthalmol       Date:  2017-06-18       Impact factor: 1.779

6.  The efficacy of autologous serum eye drops for severe dry eye syndrome: a randomized double-blind crossover study.

Authors:  Ali Riza Cenk Celebi; Cemalettin Ulusoy; G Ertugrul Mirza
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-25       Impact factor: 3.117

7.  Fingerprick autologous blood: a novel treatment for dry eye syndrome.

Authors:  J Than; S Balal; J Wawrzynski; N Nesaratnam; G M Saleh; J Moore; A Patel; S Shah; B Sharma; B Kumar; J Smith; A Sharma
Journal:  Eye (Lond)       Date:  2017-06-16       Impact factor: 3.775

Review 8.  Autologous serum eye drops for ocular surface disorders.

Authors:  G Geerling; S Maclennan; D Hartwig
Journal:  Br J Ophthalmol       Date:  2004-11       Impact factor: 4.638

9.  Liquid nitrogen cryotherapy for surface eye disease (an AOS thesis).

Authors:  Frederick Web Fraunfelder
Journal:  Trans Am Ophthalmol Soc       Date:  2008

10.  Albumin as a tear supplement in the treatment of severe dry eye.

Authors:  S Shimmura; R Ueno; Y Matsumoto; E Goto; A Higuchi; J Shimazaki; K Tsubota
Journal:  Br J Ophthalmol       Date:  2003-10       Impact factor: 4.638

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