Literature DB >> 1167942

Enhancement of the electrical excitability of neuroblastoma cells by valinomycin.

I Spector, C Palfrey, U Z Littauer.   

Abstract

Mouse neuroblastoma cells in stationary phase of growth display partially developed electrical properties. Addition of the K+ selective carrier valinomycin to these cells causes rapid enhancement of electrical excitability. We suggest that the appearance of molecules with properties similar to valinomycin is essential for the full expression of electrical excitability in differentiating neuroblastoma.

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Year:  1975        PMID： 1167942     DOI： 10.1038/254121a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  4 in total

1.  Maturation of neuroblastoma cells in the presence of dimethylsulfoxide.

Authors:  Y Kimhi; C Palfrey; I Spector; Y Barak; U Z Littauer
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

2.  Assessment of murine neuroblastoma (N1E-115) resting membrane potential by confocal microscopy.

Authors:  M Hernandez; W S Kisaalita; M A Farmer
Journal:  J Fluoresc       Date:  1996-06       Impact factor: 2.217

3.  A potassium ionophore (valinomycin) inhibits lymphocyte proliferation by its effects on the cell membrane.

Authors:  R P Daniele; S K Holian
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

4.  In vitro effect of liposome-incorporated valinomycin on growth and macromolecular synthesis of normal and ras-transformed 3T3 cells.

Authors:  S S Daoud; R L Juliano
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333
  4 in total

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