Literature DB >> 11678668

(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.

L F Villegas1, A Marçalo, J Martin, I D Fernández, H Maldonado, A J Vaisberg, G B Hammond.   

Abstract

Bioassay-guided investigation of the ethanol extract of Peperomia galioides using a tensile strength method in mice as a monitor led to the isolation of epi-alpha-bisabolol (1) (ED(50) 155 microg/mL). An in vivo healing study of selected commercially available monoterpenoids yielded two bioactive compounds, alpha-bisabolol (2) and alpha-terpineol (3) (ED(50) of 228 and 240 microg/g mouse[corrected], respectively).

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Year:  2001        PMID： 11678668     DOI： 10.1021/np0102859

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Seed germination, phenology, and antiedematogenic activity of Peperomia pellucida (L.) H. B. K.

Authors:  Maria de Fátima Arrigoni-Blank; Ricardo Luiz Barros Oliveira; Sandra Santos Mendes; Paulo de Albuquerque Silva; Angelo Roberto Antoniolli; Jeane Carvalho Vilar; Sócrates Cabral de Holanda Cavalcanti; Arie Fitzgerald Blank
Journal:  BMC Pharmacol       Date:  2002-05-09

Review 2.  A multipronged approach to the study of peruvian ethnomedicinal plants: a legacy of the ICBG-Peru Project.

Authors:  José C Aponte; Abraham J Vaisberg; Rosario Rojas; Michel Sauvain; Walter H Lewis; Gerardo Lamas; César Sarasara; Robert H Gilman; Gerald B Hammond
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

3.  Attenuation of visceral nociception by α-bisabolol in mice: investigation of mechanisms.

Authors:  Gerlânia de Oliveira Leite; Cícera Norma Fernandes; Irwin Rose Alencar de Menezes; José Galberto Martins da Costa; Adriana Rolim Campos
Journal:  Org Med Chem Lett       Date:  2012-05-21

Review 4.  Analgesic-Like Activity of Essential Oil Constituents: An Update.

Authors:  Rita de Cássia da Silveira E Sá; Tamires Cardoso Lima; Flávio Rogério da Nóbrega; Anna Emmanuela Medeiros de Brito; Damião Pergentino de Sousa
Journal:  Int J Mol Sci       Date:  2017-12-09       Impact factor: 5.923

Review 5.  A systematic review of the wound-healing effects of monoterpenes and iridoid derivatives.

Authors:  Rosana S S Barreto; Ricardo L C Albuquerque-Júnior; Adriano A S Araújo; Jackson R G S Almeida; Márcio R V Santos; André S Barreto; Josimari M DeSantana; Pollyana S Siqueira-Lima; Jullyana S S Quintans; Lucindo J Quintans-Júnior
Journal:  Molecules       Date:  2014-01-13       Impact factor: 4.411

Review 6.  Challenges in Healing Wound: Role of Complementary and Alternative Medicine.

Authors:  Prakash Monika; Mathikere Naganna Chandraprabha; Annapoorni Rangarajan; P Veena Waiker; Kotamballi N Chidambara Murthy
Journal:  Front Nutr       Date:  2022-01-20

Review 7.  Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol.

Authors:  Lujain Bader Eddin; Niraj Kumar Jha; Sameer N Goyal; Yogeeta O Agrawal; Sandeep B Subramanya; Salim M A Bastaki; Shreesh Ojha
Journal:  Nutrients       Date:  2022-03-25       Impact factor: 5.717

8.  In Vitro Antileishmanial Activity of Essential Oil of Vanillosmopsis arborea (Asteraceae) Baker.

Authors:  Aracélio Viana Colares; Fernando Almeida-Souza; Noemi Nosomi Taniwaki; Celeste da Silva Freitas Souza; José Galberto Martins da Costa; Kátia da Silva Calabrese; Ana Lúcia Abreu-Silva
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-09       Impact factor: 2.629

Review 9.  Wound Healing: Biologics, Skin Substitutes, Biomembranes and Scaffolds.

Authors:  Krishna S Vyas; Henry C Vasconez
Journal:  Healthcare (Basel)       Date:  2014-09-10

10.  α-Bisabolol, a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced Rat Model of Parkinson's disease.

Authors:  Hayate Javed; M F Nagoor Meeran; Sheikh Azimullah; Lujain Bader Eddin; Vivek Dhar Dwivedi; Niraj Kumar Jha; Shreesh Ojha
Journal:  Biomolecules       Date:  2020-10-08
  10 in total

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