Literature DB >> 11678667

Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa.

A Casapullo1, A Cutignano, I Bruno, G Bifulco, C Debitus, L Gomez-Paloma, R Riccio.   

Abstract

A new pyrroloiminoquinone alkaloid (1) belonging to the makaluvamine family has been isolated from the sponge Zyzzya cf. fuliginosa collected in the waters off the Vanuatu Islands. The compound, designated makulavamine P, was characterized on the basis of its spectral data and displayed cytoxicity in the microM range on KB cells and antioxidant activity.

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Year:  2001        PMID： 11678667     DOI： 10.1021/np010053+

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

1.  Total synthesis of zyzzyanones A-D.

Authors:  Dwayaja H Nadkarni; Srinivasan Murugesan; Sadanandan E Velu
Journal:  Tetrahedron       Date:  2013-05-20       Impact factor: 2.457

2.  Study of molecular interactions by hydrogen bond of charged forms of makaluvamines and complex stability with H2O and glutamic acid (Glu Ac) by the theory of the functional of density (B3LYP).

Authors:  Sékou Diomandé; Affoué Lucie Bédé; Soleymane Koné; El-Hadji Sawaliho Bamba
Journal:  J Mol Model       Date:  2019-11-13       Impact factor: 1.810

3.  A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids.

Authors:  Srinivasan Murugesan; Dwayaja H Nadkarni; Sadanandan E Velu
Journal:  Tetrahedron Lett       Date:  2009-06-24       Impact factor: 2.415

4.  Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Authors:  Scharri J Ezell; Haibo Li; Hongxia Xu; Xiangrong Zhang; Evrim Gurpinar; Xu Zhang; Elizabeth R Rayburn; Charnell I Sommers; Xinyi Yang; Sadanandan E Velu; Wei Wang; Ruiwen Zhang
Journal:  Mar Drugs       Date:  2010-07-13       Impact factor: 5.118

Review 5.  Recent advances in isolation, synthesis, and evaluation of bioactivities of bispyrroloquinone alkaloids of marine origin.

Authors:  Bhavitavya Nijampatnam; Shilpa Dutta; Sadanandan E Velu
Journal:  Chin J Nat Med       Date:  2015-08

6.  FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Authors:  Feng Wang; Scharri J Ezell; Yong Zhang; Wei Wang; Elizabeth R Rayburn; Dwayaja H Nadkarni; Srinivasan Murugesan; Sadanandan E Velu; Ruiwen Zhang
Journal:  Invest New Drugs       Date:  2009-03-10       Impact factor: 3.850

7.  Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

Authors:  Bidhan A Shinkre; Kevin P Raisch; Liming Fan; Sadanandan E Velu
Journal:  Bioorg Med Chem Lett       Date:  2007-02-25       Impact factor: 2.823

8.  Experimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.

Authors:  Tao Chen; Yi Xu; He Guo; Yanling Liu; Pingting Hu; Xinying Yang; Xiaoguang Li; Shichao Ge; Sadanandan E Velu; Dwayaja H Nadkarni; Wei Wang; Ruiwen Zhang; Hui Wang
Journal:  PLoS One       Date:  2011-06-06       Impact factor: 3.240

9.  Evaluation of the Antioxidant Activity of the Marine Pyrroloiminoquinone Makaluvamines.

Authors:  Eva Alonso; Rebeca Alvariño; Marta Leirós; Jioji N Tabudravu; Klaus Feussner; Miriam A Dam; Mostafa E Rateb; Marcel Jaspars; Luis M Botana
Journal:  Mar Drugs       Date:  2016-10-27       Impact factor: 5.118

Review 10.  An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs.

Authors:  Verónica Ruiz-Torres; Jose Antonio Encinar; María Herranz-López; Almudena Pérez-Sánchez; Vicente Galiano; Enrique Barrajón-Catalán; Vicente Micol
Journal:  Molecules       Date:  2017-06-23       Impact factor: 4.411
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