Application of Lagrangian particle transport model to tuberculosis (TB) bacteria UV dosing in a ventilated isolation room.

The aim of this work is to define the basis for design guidelines that will minimise the risk of exposure from airborne organisms in hospital isolation rooms. This research employs an algorithm that combines an understanding of the interaction between the room airflow and the ultra violet (UV) system. The airflow in such a room is complex and therefore cannot easily be accounted for by existing design guidance. The main findings were firstly, the mean lifetime of the ventilated particles does not reduce in proportion with increasing ventilation rate. Secondly, an increase in the ventilation rate reduces the effectiveness of ultra violet germicidal irradiation (UVGI) with only a limited increase in the number of particles that are ventilated. Finally, there is a social benefit attached to this project from the point of view of helping people who are vulnerable as well as reducing their risk of being exposed to possible tuberculosis infection. The significance of these findings is to provide the engineer and the architect with an essential tool to ensure good design practice. It is also important to ensure that the methodology can be applicable to most isolation room uses.