Combined craniofacial resection for malignant disease.

A combined craniofacial approach has been employed in nineteen patients with tumors involving the base of the skull. Monoblock resection of the temporal bone, anterior fossa, or anterior and middle fossa can be achieved with acceptable mortality, even in cases of advanced cancer that recurs after radiation. Immediate reconstruction with a full thickness flap was routinely employed to provide improved cosmesis and to minimize the risk of intracranial infection.