Literature DB >> 116282

The effect of high dose oxprenolol on stress-induced physical and psychophysiological variables.

N Farhoumand, J Harrison, C M Pare, P Turner, S Wynn.   

Abstract

The effects of oral oxprenolol (480 mg) and lorazepam (2 mg) on skin conductance, reaction time, critical flicker frequency and self-rating visual analogue scales for anxiety, sedation and concentration were investigated in 6 healthy male volunteers. Oxprenolol exerted a central action similar to lorazepam as shown by a significant lowering of skin conductance and decrease in the number of spontaneous fluctuations during stress, impaired critical flicker frequency and decrease in alertness with reduced concentration.

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Year:  1979        PMID： 116282     DOI： 10.1007/bf00427526

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  12 in total

1.  Direct evidence for an interaction of beta-adrenergic blockers with the 5-HT receptor.

Authors: 
Journal:  Nature       Date:  1977-05-19       Impact factor: 49.962

2.  Computer analysed EEG and behavioral changes after psychoactive drugs.

Authors:  J Roubicek; M Matejcek; R Porsolt
Journal:  Int J Neurol       Date:  1975

3.  THE BEHAVIOUR OF THE PALMAR SWEAT GLANDS IN STRESS.

Authors:  J HARRISON
Journal:  J Psychosom Res       Date:  1964-12       Impact factor: 3.006

4.  Propranolol on tests of visual function and central nervous activity.

Authors:  P C Bryan; D O Efiong; J Stewart-Jones; P Turner
Journal:  Br J Clin Pharmacol       Date:  1974-02       Impact factor: 4.335

5.  Effects of beta adrenergic blockade with sotalol in chronic anxiety.

Authors:  P J Tyrer; M H Lader
Journal:  Clin Pharmacol Ther       Date:  1973 May-Jun       Impact factor: 6.875

6.  Unwanted effects of propranolol.

Authors:  S A Stephen
Journal:  Am J Cardiol       Date:  1966-09       Impact factor: 2.778

7.  The effects of high doses of oxprenolol and of propranolol on pursuit rotor performance, reaction time and critical flicker frequency.

Authors:  C W Ogle; P Turner; H Markomihelakis
Journal:  Psychopharmacologia       Date:  1976-04-15

8.  Reduced respiratory responses to carbon dioxide after propranolol: a central action.

Authors:  C P Mustchin; H R Gribbin; A E Tattersfield; C F George
Journal:  Br Med J       Date:  1976-11-20

9.  USE OF PROPRANOLOL (INDERAL) IN TREATMENT OF HYPERTENSION.

Authors:  B N PRICHARD; P M GILLAM
Journal:  Br Med J       Date:  1964-09-19

10.  Central and peripheral effects of propranolol and sotalol in normal human subjects.

Authors:  M H Lader; P J Tyrer
Journal:  Br J Pharmacol       Date:  1972-07       Impact factor: 8.739
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  5 in total

1.  Anxiolytic effects of acebutolol and atenolol in healthy volunteers with induced anxiety.

Authors:  S G Kilminster; M J Lewis; D M Jones
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

Review 2.  Psychomotor performance and antihypertensive treatment.

Authors:  L Kalra; C G Swift; S H Jackson
Journal:  Br J Clin Pharmacol       Date:  1994-02       Impact factor: 4.335

Review 3.  Psychomotor function and psychoactive drugs.

Authors:  I Hindmarch
Journal:  Br J Clin Pharmacol       Date:  1980-09       Impact factor: 4.335

4.  Tests of autonomic function in assessing centrally-acting drugs.

Authors:  P Turner
Journal:  Br J Clin Pharmacol       Date:  1980-08       Impact factor: 4.335

5.  The effects of clobazam and lorazepam on aspects of psychomotor performance and car handling ability.

Authors:  I Hindmarch; A C Gudgeon
Journal:  Br J Clin Pharmacol       Date:  1980-08       Impact factor: 4.335
  5 in total

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