Literature DB >> 11603546

Bleeding hepatic adenoma: expectant treatment to limit the extent of liver resection.

B Heeringa1, A Sardi.   

Abstract

Hepatic adenomas (HAs) are benign but can present as an acute surgical emergency. The relationship between HA and oral contraceptives (OCs) has been well documented and there have been several reports of tumor regression after the withdrawal of hormonal agents. However, not all HAs regress in this manner; have been reported to remain stable, increase in size, hemorrhage, or rarely, undergo malignant transformation. Given the unpredictable nature of these lesions they are generally treated surgically. In July 1995 a patient with a 6-year history of OC use was admitted with a history of sudden-onset right upper quadrant abdominal pain of 2 days' duration. The clinical picture and imaging studies led to the diagnosis of a bleeding hepatic adenoma without rupture. She was treated expectantly for a period of 14 months before surgery. This allowed the tumor to significantly decrease in size and thus limit the extent of resection. If the patient presented in this case had undergone surgery at the time of initial diagnosis a right hepatic lobectomy as opposed to a wedge resection would have been required. Treating this patient expectantly significantly decreased the potential morbidity associated with a larger resection.

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Year:  2001        PMID: 11603546

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  3 in total

1.  Open and laparoscopic resection of hepatocellular adenoma: trends over 23 years at a specialist hepatobiliary unit.

Authors:  Nicola de'Angelis; Riccardo Memeo; Julien Calderaro; Emanuele Felli; Chady Salloum; Philippe Compagnon; Alain Luciani; Alexis Laurent; Daniel Cherqui; Daniel Azoulay
Journal:  HPB (Oxford)       Date:  2014-05-23       Impact factor: 3.647

Review 2.  Malignant transformation of hepatocellular adenomas into hepatocellular carcinomas: a systematic review including more than 1600 adenoma cases.

Authors:  Jan H M B Stoot; Robert J S Coelen; Mechteld C De Jong; Cornelis H C Dejong
Journal:  HPB (Oxford)       Date:  2010-10       Impact factor: 3.647

3.  Liver cell adenoma and liver cell adenomatosis.

Authors:  Ludger Barthelmes; Iain S Tait
Journal:  HPB (Oxford)       Date:  2005       Impact factor: 3.647

  3 in total

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